PDB entry 1u8c

View 1u8c on RCSB PDB site
Description: A novel adaptation of the integrin PSI domain revealed from its crystal structure
Class: cell adhesion
Keywords: PSI domain, integrin, vitronectrin receptor
Deposited on 2004-08-05, released 2004-12-28
The last revision prior to the SCOP 1.75 freeze date was dated 2004-12-28, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.293
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Integrin alpha-V
    Species: HOMO SAPIENS
    Gene: ITGAV, VNRA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06756 (0-End)
      • see remark 999 (752)
    Domains in SCOP 1.75: d1u8ca1, d1u8ca2, d1u8ca3, d1u8ca4
  • Chain 'B':
    Compound: integrin beta-3
    Species: HOMO SAPIENS
    Gene: ITGB3, GP3A
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1u8cb1, d1u8cb2, d1u8cb3, d1u8cb4, d1u8cb5, d1u8cb6
  • Heterogens: NAG, NDG, CA

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u8cA (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarsmppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldcgedn
vckpklevsvdsdqkkiyigddnpltlivkaqnqgegayeaelivsiplqadfigvvrnn
ealarlscafktenqtrqvvcdlgnpmkagtqllaglrfsvhqqsemdtsvkfdlqiqss
nlfdkvspvvshkvdlavlaaveirgvsspdhvflpipnwehkenpeteedvgpvvqhiy
elrnngpssfskamlhlqwpykynnntllyilhydidgpmnctsdmeinplrikisslqt
tekndtvagqgerdhlitkrdlalsegdihtlgcgvaqclkivcqvgrldrgksailyvk
sllwtetfmnkenqnhsyslkssasfnviefpyknlpieditnstlvttnvtwgiqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1u8cA (A:)
fnldvdspaeysgpegsyfgfavdffvpsassrmfllvgapkanttqpgiveggqvlkcd
wsstrrcqpiefdatgnrdyakddplefkshqwfgasvrskqdkilacaplyhwrtemkq
erepvgtcflqdgtktveyapcrsqdidadgqgfcqggfsidftkadrvllggpgsfywq
gqlisdqvaeivskydpnvysikynnqlatrtaqaifddsylgysvavgdfngdgiddfv
sgvpraartlgmvyiydgknmsslynftgeqmaayfgfsvaatdingddyadvfigaplf
mdrgsdgklqevgqvsvslqrasgdfqttklngfevfarfgsaiaplgdldqdgfndiai
aapyggedkkgivyifngrstglnavpsqilegqwaarsmppsfgysmkgatdidkngyp
dlivgafgvdrailyrarpvitvnaglevypsilnqdnktcslpgtalkvscfnvrfclk
adgkgvlprklnfqvellldklkqkgairralflysrspshsknmtisrgglmqceelia
ylrdesefrdkltpitifmeyrldyrtaadttglqpilnqftpanisrqahilldcgedn
vckpklevsvdsdqkkiyigddnpltlivkaqnqgegayeaelivsiplqadfigvvrnn
ealarlscafktenqtrqvvcdlgnpmkagtqllaglrfsvhqqsemdtsvkfdlqiqss
nlfdkvspvvshkvdlavlaaveirgvsspdhvflpipnwehkenpeteedvgpvvqhiy
elrnngpssfskamlhlqwpykynnntllyilhydidgpmnctsdmeinplrikissldi
htlgcgvaqclkivcqvgrldrgksailyvksllwtetfmnkenqnhsyslkssasfnvi
efpyknlpieditnstlvttnvtwgiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u8cB (B:)
gpnicttrgvsscqqclavspmcawcsdealplgsprcdlkenllkdncapesiefpvse
arvledrplsdkgsgdssqvtqvspqrialrlrpddsknfsiqvrqvedypvdiyylmdl
sysmkddlwsiqnlgtklatqmrkltsnlrigfgafvdkpvspymyisppealenpcydm
kttclpmfgykhvltltdqvtrfneevkkqsvsrnrdapeggfdaimqatvcdekigwrn
dashllvfttdakthialdgrlagivqpndgqchvgsdnhysasttmdypslglmtekls
qkninlifavtenvvnlyqnyselipgttvgvlsmdssnvlqlivdaygkirskvelevr
dlpeelslsfnatclnnevipglkscmglkigdtvsfsieakvrgcpqekeksftikpvg
fkdslivqvtfdcdcacqaqaepnshrcnngngtfecgvcrcgpgwlgsqcecseedyrp
sqqdecspregqpvcsqrgeclcgqcvchssdfgkitgkycecddfscvrykgemcsghg
qcscgdclcdsdwtgyycncttrtdtcmssngllcsgrgkcecgscvciqpgsygdtcek
cptcpdactfkkecveckkfdrepymtentcnrycrdeiesvkelkdtgkdavnctykne
ddcvvrfqyyedssgksilyvveepecpkgpd

    Sequence, based on observed residues (ATOM records): (download) 
    >1u8cB (B:)
gpnicttrgvsscqqclavspmcawcsdealplgsprcdlkenllkdncaiefpvsearv
ledrplsdkgsgdssqvtqvspqrialrlrpddsknfsiqvrqvedypvdiyylmdlsys
mkddlwsiqnlgtklatqmrkltsnlrigfgafvdkpvspymyisppealenpcydmktt
clpmfgykhvltltdqvtrfneevkkqsvsrnrdapeggfdaimqatvcdekigwrndas
hllvfttdakthialdgrlagivqpndgqchvgsdnhysasttmdypslglmteklsqkn
inlifavtenvvnlyqnyselipgttvgvlsmdssnvlqlivdaygkirskvelevrdlp
eelslsfnatclnnevipglkscmglkigdtvsfsieakvrgcpqekeksftikpvgfkd
slivqvtfdcdcddfscvrykgemcsghgqcscgdclcdsdwtgyycncttrtdtcmssn
gllcsgrgkcecgscvciqpgsygdtcekcptcpdactfkkecveckkfdrepymtentc
nrycrdeiesvkelkdtgkdavnctykneddcvvrfqyyedssgksilyvveepecpkg