PDB entry 1u6g

View 1u6g on RCSB PDB site
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Class: ligase
Keywords: cullin repeat, heat repeat, ring finger, ligase
Deposited on 2004-07-29, released 2004-12-14
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.243
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cullin homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CUL1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1u6ga1, d1u6ga2, d1u6ga3
  • Chain 'B':
    Compound: RING-box protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: Rbx1, ROC1, RNF75
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1u6gb_
  • Chain 'C':
    Compound: TIP120 protein
    Species: Homo sapiens [TaxId:9606]
    Gene: Cand1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1u6gc_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1u6gA (A:)
msstrsqnphglkqigldqiwddlragiqqvytrqsmaksrymelythvynyctsvhqsn
qargagvppskskkgqtpggaqfvglelykrlkeflknyltnllkdgedlmdesvlkfyt
qqwedyrfsskvlngicaylnrhwvrrecdegrkgiyeiyslalvtwrdclfrplnkqvt
navlkliekerngetintrlisgvvqsyvelglneddafakgptltvykesfesqfladt
erfytresteflqqnpvteymkkaearlleeqrrvqvylhestqdelarkceqvliekhl
eifhtefqnlldadknedlgrmynlvsriqdglgelkkllethihnqglaaiekcgeaal
ndpkmyvqtvldvhkkynalvmsafnndagfvaaldkacgrfinnnavtkmaqssskspe
llarycdsllkkssknpeeaeledtlnqvmvvfkyiedkdvfqkfyakmlakrlvhqnsa
sddaeasmisklkqacgfeytsklqrmfqdigvskdlneqfkkhltnsepldldfsiqvl
ssgswpfqqsctfalpselersyqrftafyasrhsgrkltwlyqlskgelvtncfknryt
lqastfqmaillqyntedaytvqqltdstqikmdilaqvlqillkskllvledenanvde
velkpdtliklylgyknkklrvninvpmkteqkqeqetthknieedrklliqaaivrimk
mrkvlkhqqllgevltqlssrfkprvpvikkcidiliekeylervdgekdtysyla

    Sequence, based on observed residues (ATOM records): (download) 
    >1u6gA (A:)
ldqiwddlragiqqvytrqsmaksrymelythvynyctsvglelykrlkeflknyltnll
kdgedlmdesvlkfytqqwedyrfsskvlngicaylnrhwvrreckgiyeiyslalvtwr
dclfrplnkqvtnavlkliekerngetintrlisgvvqsyvelglgptltvykesfesqf
ladterfytresteflqqnpvteymkkaearlleeqrrvqvylhestqdelarkceqvli
ekhleifhtefqnlldadknedlgrmynlvsriqdglgelkkllethihnqglaaiekcg
eaalndpkmyvqtvldvhkkynalvmsafnndagfvaaldkacgrfinnnavtkmaqsss
kspellarycdsllkkeeaeledtlnqvmvvfkyiedkdvfqkfyakmlakrlvhqnsas
ddaeasmisklkqacgfeytsklqrmfqdigvskdlneqfkkhltnsepldldfsiqvls
sgswpfqqsctfalpselersyqrftafyasrhsgrkltwlyqlskgelvtncfknrytl
qastfqmaillqyntedaytvqqltdstqikmdilaqvlqillkskllvledenanvdev
elkpdtliklylgyknkklrvninvpmkteqkqeqetthknieedrklliqaaivrimkm
rkvlkhqqllgevltqlssrfkprvpvikkcidiliekeylervdgekdtysyla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1u6gB (B:)
maaamdvdtpsgtnsgagkkrfevkkwnavalwawdivvdncaicrnhimdlciecqanq
asatseectvawgvcnhafhfhcisrwlktrqvcpldnrewefqkygh

    Sequence, based on observed residues (ATOM records): (download) 
    >1u6gB (B:)
kkrfevkkwnavalwawdivvdncaicrnhimdlciecqanqasatseectvawgvcnha
fhfhcisrwlktrqvcpldnrewefqky

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1u6gC (C:)
masasyhisnllekmtssdkdfrfmatndlmtelqkdsikldddserkvvkmilklledk
ngevqnlavkclgplvskvkeyqvetivdtlctnmlsdkeqlrdissiglktvigelppa
ssgsalaanvckkitgrltsaiakqedvsvqlealdimadmlsrqggllvnfhpsiltcl
lpqltsprlavrkrtiialghlvmscgnivfvdliehllselskndsmsttrtyiqciaa
isrqaghrigeylekiiplvvkfcnvdddelreyciqafesfvrrcpkevyphvstiini
clkyltydpnynyddededenamdadggddddqgsddeysddddmswkvrraaakcldav
vstrhemlpefyktvspalisrfkereenvkadvfhaylsllkqtrpvqswlcdpdameq
getpltmlqsqvpnivkalhkqmkeksvktrqccfnmltelvnvlpgaltqhipvlvpgi
ifslndkssssnlkidalsclyvilcnhspqvfhphvqalvppvvacvgdpfykitseal
lvtqqlvkvirpldqpssfdatpyikdlftctikrlkaadidqevkeraiscmgqiicnl
gdnlgsdlpntlqiflerlkneitrlttvkaltliagsplkidlrpvlgegvpilasflr
knqralklgtlsaldiliknysdsltaamidavldelpplisesdmhvsqmaisflttla
kvypsslskisgsilneliglvrspllqggalsamldffqalvvtgtnnlgymdllrmlt
gpvysqstalthkqsyysiakcvaaltracpkegpavvgqfiqdvknsrstdsirllall
slgevghhidlsgqlelksvileafsspseevksaasyalgsisvgnlpeylpfvlqeit
sqpkrqylllhslkeiissasvvglkpyveniwalllkhcecaeegtrnvvaeclgkltl
idpetllprlkgylisgssyarssvvtavkftisdhpqpidpllkncigdflktledpdl
nvrrvalvtfnsaahnkpslirdlldtvlphlynetkvrkelirevemgpfkhtvddgld
irkaafecmytlldscldrldifeflnhvedglkdhydikmltflmlvrlstlcpsavlq
rldrlveplratcttkvkansvkqefekqdelkrsamravaalltipeaeksplmsefqs
qissnpelaaifesiqkdssstnlesmdts

    Sequence, based on observed residues (ATOM records): (download) 
    >1u6gC (C:)
asyhisnllekmtssdkdfrfmatndlmtelqkdsikldddserkvvkmilklledknge
vqnlavkclgplvskvkeyqvetivdtlctnmlsdkeqlrdissiglktvigelpsalaa
nvckkitgrltsaiakqedvsvqlealdimadmlsrqggllvnfhpsiltcllpqltspr
lavrkrtiialghlvmscfvdliehllselskndsmsttrtyiqciaaisrqaghrigey
lekiiplvvkfcnvdddelreyciqafesfvrrcpkevyphvstiiniclkyltydmswk
vrraaakcldavvstrhemlpefyktvspalisrfkereenvkadvfhaylsllkqtrpv
getpltmlqsqvpnivkalhkqmkeksvktrqccfnmltelvnvlpgaltqhipvlvpgi
ifslndkssssnlkidalsclyvilcnhspqvfhphvqalvppvvacvgdpfykitseal
lvtqqlvkvirpldqpssfdatpyikdlftctikrlkaadidqevkeraiscmgqiicnl
gdnlgsdlpntlqiflerlkneitrlttvkaltliagsplkidlrpvlgegvpilasflr
knqralklgtlsaldiliknysdsltaamidavldelpplisesdmhvsqmaisflttla
kvypsslskisgsilneliglvrspllqggalsamldffqalvvtgtnnlgymdllrmlt
gpvysqthkqsyysiakcvaaltracpkegpavvgqfiqdvknsrstdsirllallslge
vghhidlsgqlelksvileafsspseevksaasyalgsisvgnlpeylpfvlqeitsqpk
rqylllhslkeiissasvvglkpyveniwalllkhcecaeegtrnvvaeclgkltlidpe
tllprlkgylisgssyarssvvtavkftisdhpqpidpllkncigdflktledpdlnvrr
valvtfnsaahnkpslirdlldtvlphlynetkvrkelirevemgpfkhtvddgldirka
afecmytlldscldrldifeflnhvedglkdhydikmltflmlvrlstlcpsavlqrldr
lveplratcttkvkansvkqefekqdelkrsamravaalltipeaeksplmsefqsqiss
npelaa