PDB entry 1tzi

View 1tzi on RCSB PDB site
Description: Crystal Structure of the Fab YADS2 Complexed with h-VEGF
Class: immune system
Keywords: phage display, antibody library, protein engineering
Deposited on 2004-07-10, released 2004-08-31
The last revision prior to the SCOP 1.73 freeze date was dated 2004-08-31, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.22
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fab YADS2 Light Chain
    Species: MUS MUSCULUS
    Domains in SCOP 1.73: d1tzia1, d1tzia2
  • Chain 'B':
    Compound: Fab YADS2 Heavy Chain
    Species: MUS MUSCULUS
    Domains in SCOP 1.73: d1tzib1, d1tzib2
  • Chain 'V':
    Compound: Vascular Endothelial Growth Factor A
    Species: HOMO SAPIENS
    Gene: VEGF, VEGFA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1tziv_

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tziA (A:)
diqmtqspsslsasvgdrvtitcrasqsyayavawyqqkpgkapklliydasylysgvps
rfsgsgsgtdftltisslqpedfatyycqqaysspdtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1tziB (B:)
evqlvesggglvqpggslrlscaasgfaiydydihwvrqapgkglewvadiapyagatay
adsvkgrftisadtskntaylqmnslraedtavyycsrssyayyaamdywgqgtlvtvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'V':
    Sequence, based on SEQRES records: (download) 
    >1tziV (V:)
gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1tziV (V:)
evvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpte
esnitmqimrikphqgqhigemsflqhnkcecrpkkd