PDB entry 1twi
View 1twi on RCSB PDB site
Description: Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine
Class: lyase
Keywords: antibiotic resistance, diaminopimelate decarboxylase, lysine biosynthesis, structural genomics, NYSGXRC, T135, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, LYASE
Deposited on
2004-07-01, released
2004-07-27
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.157
AEROSPACI score: 0.49
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: diaminopimelate decarboxylase
Species: Methanocaldococcus jannaschii [TaxId:2190]
Gene: LYSA, MJ1097
Database cross-references and differences (RAF-indexed):
- Uniprot Q58497 (1-433)
- initiating methionine (0)
Domains in SCOPe 2.04: d1twia1, d1twia2 - Chain 'B':
Compound: diaminopimelate decarboxylase
Species: Methanocaldococcus jannaschii [TaxId:2190]
Gene: LYSA, MJ1097
Database cross-references and differences (RAF-indexed):
- Uniprot Q58497 (1-433)
- initiating methionine (0)
Domains in SCOPe 2.04: d1twib1, d1twib2 - Chain 'C':
Compound: diaminopimelate decarboxylase
Species: Methanocaldococcus jannaschii [TaxId:2190]
Gene: LYSA, MJ1097
Database cross-references and differences (RAF-indexed):
- Uniprot Q58497 (1-433)
- initiating methionine (0)
Domains in SCOPe 2.04: d1twic1, d1twic2 - Chain 'D':
Compound: diaminopimelate decarboxylase
Species: Methanocaldococcus jannaschii [TaxId:2190]
Gene: LYSA, MJ1097
Database cross-references and differences (RAF-indexed):
- Uniprot Q58497 (1-433)
- initiating methionine (0)
Domains in SCOPe 2.04: d1twid1, d1twid2 - Heterogens: MG, LYS, PLP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1twiA (A:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1twiB (B:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1twiC (C:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1twiD (D:)
mlgndtveikdgrffidgydaielaekfgtplyvmseeqikinynryieafkrweeetgk
efivayaykananlaitrllaklgcgadvvsggelyiaklsnvpskkivfngncktkeei
imgieanirafnvdsiselilinetakelgetanvafrinpnvnpkthpkistglkknkf
gldvesgiamkaikmalemeyvnvvgvhchigsqltdispfieetrkvmdfvvelkeegi
eiedvnlggglgipyykdkqiptqkdladaiintmlkykdkvempnlilepgrslvatag
yllgkvhhiketpvtkwvmidagmndmmrpamyeayhhiinckvknekevvsiagglces
sdvfgrdreldkvevgdvlaifdvgaygismannynargrprmvltskkgvflirerety
adliakdivpphll