PDB entry 1tva

View 1tva on RCSB PDB site
Description: human DNA polymerase beta complexed with nicked DNA containing a mismatched template thymidine and incoming cytidine
Class: transferase/DNA
Keywords: NUCLEOTIDYLTRANSFERASE, DNA REPAIR, DNA MISMATCH, BASE EXCISION REPAIR, transferase/DNA COMPLEX
Deposited on 2004-06-29, released 2004-11-23
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.212
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase beta
    Species: Homo sapiens [TaxId:9606]
    Gene: POLB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1tvaa1, d1tvaa2, d1tvaa3
  • Chain 'D':
    Compound: 5'-d(p*gp*tp*cp*gp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*gp*cp*tp*gp*ap*tp*gp*cp*gp*cp*c)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*gp*ap*cp*tp*gp*cp*gp*cp*ap*tp*cp*ap*gp*c)-3'
  • Heterogens: NA, MG, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1tvaA (A:)
mskrkapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeak
klpgvgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegik
tledlrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgs
frrgaessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcq
lpskndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirp
lgvtgvageplpvdsekdifdyiqwkyrepkdrse

    Sequence, based on observed residues (ATOM records): (download) 
    >1tvaA (A:)
kapqetlnggitdmltelanfeknvsqaihkynayrkaasviakyphkiksgaeakklpg
vgtkiaekideflatgklrklekirqddtsssinfltrvsgigpsaarkfvdegiktled
lrknedklnhhqriglkyfgdfekripreemlqmqdivlnevkkvdseyiatvcgsfrrg
aessgdmdvllthpsftsestkqpkllhqvveqlqkvhfitdtlskgetkfmgvcqlpsk
ndekeyphrridirlipkdqyycgvlyftgsdifnknmrahalekgftineytirplgvt
gvageplpvdsekdifdyiqwkyrepkdrse

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.