PDB entry 1tsq

View 1tsq on RCSB PDB site
Description: crystal structure of ap2v substrate variant of nc-p1 decamer peptide in complex with v82a/d25n hiv-1 protease mutant
Class: hydrolase/viral protein
Keywords: CO-EVOLUTION, NUCLEOCAPDIS, SUBSTRATE RECOGNITION, HIV-1 PROTEASE, hydrolase-viral protein COMPLEX
Deposited on 2004-06-21, released 2005-03-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03369 (0-98)
      • engineered (6)
      • engineered (24)
      • engineered (81)
    Domains in SCOPe 2.07: d1tsqa1
  • Chain 'B':
    Compound: Pol polyprotein
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03369 (0-98)
      • engineered (6)
      • engineered (24)
      • engineered (81)
    Domains in SCOPe 2.07: d1tsqb1
  • Chain 'P':
    Compound: ap2v nc-p1 substrate peptide
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04591 (0-9)
      • see remark 999 (2)
      • engineered (9)
  • Heterogens: ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tsqA (A:)
    pqitlwkrplvtiriggqlkeallntgaddtvleemnlpgkwkpkmiggiggfikvrqyd
    qipveicghkaigtvlvgptpaniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1tsqB (B:)
    pqitlwkrplvtiriggqlkeallntgaddtvleemnlpgkwkpkmiggiggfikvrqyd
    qipveicghkaigtvlvgptpaniigrnlltqigctlnf
    

  • Chain 'P':
    No sequence available.