PDB entry 1thp
View 1thp on RCSB PDB site
Description: structure of human alpha-thrombin y225p mutant bound to d-phe-pro-arg-chloromethylketone
Class: hydrolase/hydrolase inhibitor
Keywords: serine protease, fprck, hydrolase-hydrolase inhibitor complex
Deposited on
1999-01-26, released
1999-03-03
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.198
AEROSPACI score: 0.38
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (thrombin light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1thp.1 - Chain 'B':
Compound: protein (thrombin heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1thp.1 - Heterogens: 0G6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1thpA (A:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1thpA (A:)
adcglrplfekksledkterellesyi
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1thpB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkpgfy
thvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1thpB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkpgfythvfrlkk
wiqkvidqf