PDB entry 1ted

View 1ted on RCSB PDB site
Description: Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis
Class: transferase
Keywords: thiolase fold, substrate binding tunnel
Deposited on 2004-05-25, released 2004-08-03
The last revision prior to the SCOP 1.75 freeze date was dated 2004-09-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.205
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1teda_
  • Chain 'B':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1tedb_
  • Chain 'C':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1tedc_
  • Chain 'D':
    Compound: pks18
    Species: Mycobacterium tuberculosis
    Gene: pks18
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1tedd_
  • Heterogens: MYR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1tedA (A:)
    mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
    ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
    skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
    algtatnyvrahpamkalvvcielcsvnavfaddindvvihslfgdgcaalvigasqvqe
    klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
    glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
    qqaesakaistgvafafgpgvtvegmlfdiirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tedA (A:)
    aqlppappttvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmav
    dpldakfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstg
    fiapgvdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielc
    svnavfaddindvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgiv
    lgvnhngitcelsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvr
    slgisaelaaqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtveg
    mlfdiirr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1tedB (B:)
    mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
    ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
    skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
    algtatnyvrahpamkalvvcielcsvnavfaddindvvihslfgdgcaalvigasqvqe
    klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
    glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
    qqaesakaistgvafafgpgvtvegmlfdiirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tedB (B:)
    tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
    frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
    ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnavfadd
    indvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnhngit
    celsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgisaela
    aqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdiirr
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1tedC (C:)
    mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
    ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
    skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
    algtatnyvrahpamkalvvcielcsvnavfaddindvvihslfgdgcaalvigasqvqe
    klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
    glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
    qqaesakaistgvafafgpgvtvegmlfdiirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tedC (C:)
    aqlppappttvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmav
    dpldakfdvfrrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstg
    fiapgvdvaivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielc
    svnavfaddindvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgiv
    lgvnhngitcelsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvr
    slgisaelaaqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtveg
    mlfdiirr
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1tedD (D:)
    mnvsaesgaprragqrhevglaqlppappttvavieglatgtprrvvnqsdaadrvaelf
    ldpgqreriprvyqksrittrrmavdpldakfdvfrrepatirdrmhlfyehavplavdv
    skralaglpyraaeigllvlatstgfiapgvdvaivkelglspsisrvvvnfmgcaaamn
    algtatnyvrahpamkalvvcielcsvnavfaddindvvihslfgdgcaalvigasqvqe
    klepgkvvvrssfsqlldntedgivlgvnhngitcelsenlpgyifsgvapvvtemlwdn
    glqisdidlwaihpggpkiieqsvrslgisaelaaqswdvlarfgnmlsvslifvletmv
    qqaesakaistgvafafgpgvtvegmlfdiirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1tedD (D:)
    tvavieglatgtprrvvnqsdaadrvaelgqreriprvyqksrittrrmavdpldakfdv
    frrepatirdrmhlfyehavplavdvskralaglpyraaeigllvlatstgfiapgvdva
    ivkelglspsisrvvvnfmgcaaamnalgtatnyvrahpamkalvvcielcsvnavfadd
    indvvihslfgdgcaalvigasqvqeklepgkvvvrssfsqlldntedgivlgvnhngit
    celsenlpgyifsgvapvvtemlwdnglqisdidlwaihpggpkiieqsvrslgisaela
    aqswdvlarfgnmlsvslifvletmvqqaesakaistgvafafgpgvtvegmlfdiirr