PDB entry 1tcx
View 1tcx on RCSB PDB site
Description: hiv triple mutant protease complexed with inhibitor sb203386
Class: hydrolase (acid protease)
Keywords: aids, polyprotein, hydrolase, aspartyl protease, endonuclease, RNA-directed DNA polymerase, acid protease
Deposited on
1996-06-05, released
1996-12-07
The last revision prior to the SCOP 1.75 freeze date was dated
1996-12-07, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.18
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv protease
Species: Human immunodeficiency virus
Gene: HIV-1 PROTEASE
Database cross-references and differences (RAF-indexed):
- Uniprot P04587 (0-98)
- engineered (31)
- engineered (46)
- engineered (81)
Domains in SCOP 1.75: d1tcxa_ - Chain 'B':
Compound: hiv protease
Species: Human immunodeficiency virus
Gene: HIV-1 PROTEASE
Database cross-references and differences (RAF-indexed):
- Uniprot P04587 (0-98)
- engineered (31)
- engineered (46)
- engineered (81)
Domains in SCOP 1.75: d1tcxb_ - Heterogens: IM1, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1tcxA (A:)
pqitlwqrplvtikiggqlkealldtgaddtileemslpgrwkpkmvggiggfikvrqyd
qilieicghkaigtvlvgptpiniigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1tcxB (B:)
pqitlwqrplvtikiggqlkealldtgaddtileemslpgrwkpkmvggiggfikvrqyd
qilieicghkaigtvlvgptpiniigrnlltqigctlnf