PDB entry 1t8u

View 1t8u on RCSB PDB site
Description: Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP and tetrasaccharide substrate
Class: transferase
Keywords: alpha-beta motif, substrate-binding cleft, transferase
Deposited on 2004-05-13, released 2004-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
    Species: Homo sapiens [TaxId:9606]
    Gene: h3-OST-3
    Database cross-references and differences (RAF-indexed):
    • GB NP_006033 (4-271)
      • cloning artifact (1-3)
    Domains in SCOPe 2.08: d1t8ua1, d1t8ua2
  • Chain 'B':
    Compound: heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
    Species: Homo sapiens [TaxId:9606]
    Gene: h3-OST-3
    Database cross-references and differences (RAF-indexed):
    • GB NP_006033 (4-271)
      • cloning artifact (1-3)
    Domains in SCOPe 2.08: d1t8ub1, d1t8ub2
  • Heterogens: SO4, NA, A3P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t8uA (A:)
gpnsgtlallldegskqlpqaiiigvkkggtralleflrvhpdvravgaephffdrsydk
glawyrdlmprtldgqitmektpsyfvtreaparisamskdtklivvvrdpvtraisdyt
qtlskrpdiptfesltfknrtaglidtswsaiqigiyakhlehwlrhfpirqmlfvsger
lisdpagelgrvqdflglkriitdkhfyfnktkgfpclkkaegssrphclgktkgrthpe
idrevvrrlrefyrpfnlkfyqmtghdfgwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8uA (A:)
pnsgtlallldegskqlpqaiiigvkkggtralleflrvhpdvravgaephffdrsydkg
lawyrdlmprtldgqitmektpsyfvtreaparisamskdtklivvvrdpvtraisdytq
tlskrpdiptfesltfknglidtswsaiqigiyakhlehwlrhfpirqmlfvsgerlisd
pagelgrvqdflglkriitdkhfyfnktkgfpclkkaegssrphclgktkgrthpeidre
vvrrlrefyrpfnlkfyqmtghdfgwdg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1t8uB (B:)
gpnsgtlallldegskqlpqaiiigvkkggtralleflrvhpdvravgaephffdrsydk
glawyrdlmprtldgqitmektpsyfvtreaparisamskdtklivvvrdpvtraisdyt
qtlskrpdiptfesltfknrtaglidtswsaiqigiyakhlehwlrhfpirqmlfvsger
lisdpagelgrvqdflglkriitdkhfyfnktkgfpclkkaegssrphclgktkgrthpe
idrevvrrlrefyrpfnlkfyqmtghdfgwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1t8uB (B:)
pnsgtlallldegskqlpqaiiigvkkggtralleflrvhpdvravgaephffdrsydkg
lawyrdlmprtldgqitmektpsyfvtreaparisamskdtklivvvrdpvtraisdytq
tlskrpdiptfesltfknrtaglidtswsaiqigiyakhlehwlrhfpirqmlfvsgerl
isdpagelgrvqdflglkriitdkhfyfnktkgfpclkkaegssrphclgktkgrthpei
drevvrrlrefyrpfnlkfyqmtghdfgwdg