PDB entry 1t5w

View 1t5w on RCSB PDB site
Description: HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR)
Class: immune system
Keywords: MHC class II; najor histocompatibility complex protein; HLA-DR1; antigen; peptide
Deposited on 2004-05-05, released 2004-08-17
The last revision prior to the SCOP 1.75 freeze date was dated 2005-02-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.231
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: HOMO SAPIENS
    Gene: HLA-DRA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t5wa1, d1t5wa2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: HOMO SAPIENS
    Gene: HLA-DRB1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t5wb1, d1t5wb2
  • Chain 'C':
    Compound: 15-mer peptide fragment of Regulatory protein MIG1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27705 (7-End)
      • insertion (0-6)
  • Chain 'D':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: HOMO SAPIENS
    Gene: HLA-DRA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t5wd1, d1t5wd2
  • Chain 'E':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: HOMO SAPIENS
    Gene: HLA-DRB1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t5we1, d1t5we2
  • Chain 'F':
    Compound: 15-mer peptide fragment of Regulatory protein MIG1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27705 (7-End)
      • insertion (0-6)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1t5wA (A:)
keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1t5wB (B:)
gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewra

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1t5wD (D:)
keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

    Sequence, based on observed residues (ATOM records): (download) 
    >1t5wD (D:)
eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
rngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1t5wE (E:)
gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewra

  • Chain 'F':
    No sequence available.