PDB entry 1t5c

View 1t5c on RCSB PDB site
Description: Crystal structure of the motor domain of human kinetochore protein CENP-E
Class: contractile protein
Keywords: kinesin motor-domain-ADP complex, stranded beta-sheet core with solvent exposed alpha-helices, arrow-head shape, Structural Proteomics in Europe, SPINE, Structural Genomics, CONTRACTILE PROTEIN
Deposited on 2004-05-04, released 2005-05-10
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.228
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Centromeric protein E
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02224
      • see remark 999 (298)
    Domains in SCOPe 2.03: d1t5ca_
  • Chain 'B':
    Compound: Centromeric protein E
    Species: Homo sapiens [TaxId:9606]
    Gene: CENPE
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q02224
      • see remark 999 (298)
    Domains in SCOPe 2.03: d1t5cb_
  • Heterogens: MG, NO3, ADP, PIN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1t5cA (A:)
aeegavavcvrvrplnsreeslgetaqvywktdnnviyqvdgsksfnfdrvfhgnettkn
vyeeiaapiidsaiqgyngtifaygqtasgktytmmgsedhlgvipraihdifqkikkfp
drefllrvsymeiynetitdllcgtqkmkpliiredvnrnvyvadlteevvytsemalkw
itkgeksrhygetkmnqrssrshtifrmilesrekgepsncegsvkvshlnlvdlagser
aaqtgaagvrlkegcninrslfilgqvikklsdgqvggfinyrdskltrilqnslggnak
triictitpvsfdetltalqfastakymkntpyvnevstdelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t5cA (A:)
egavavcvrvrplnsreeslgetaqvywktdnnviyqvdgsksfnfdrvfhgnettknvy
eeiaapiidsaiqgyngtifaygqtasgktytmmgsedhlgvipraihdifqkikkfpdr
efllrvsymeiynetitdllcgtqkmkpliiredvnrnvyvadlteevvytsemalkwit
kgeksrhygetkmnqrssrshtifrmilesrekgsvkvshlnlvdlagseraarlkegcn
inrslfilgqvikklsdgqvggfinyrdskltrilqnslggnaktriictitpvsfdetl
talqfastakymkntpyvnevs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1t5cB (B:)
aeegavavcvrvrplnsreeslgetaqvywktdnnviyqvdgsksfnfdrvfhgnettkn
vyeeiaapiidsaiqgyngtifaygqtasgktytmmgsedhlgvipraihdifqkikkfp
drefllrvsymeiynetitdllcgtqkmkpliiredvnrnvyvadlteevvytsemalkw
itkgeksrhygetkmnqrssrshtifrmilesrekgepsncegsvkvshlnlvdlagser
aaqtgaagvrlkegcninrslfilgqvikklsdgqvggfinyrdskltrilqnslggnak
triictitpvsfdetltalqfastakymkntpyvnevstdelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1t5cB (B:)
gavavcvrvrplnaqvywktdnnviyqvdgsksfnfdrvfhgnettknvyeeiaapiids
aiqgyngtifaygqtasgktytmmgsedhlgvipraihdifqkikkfpdrefllrvsyme
iynetitdllcgtqkmkpliiredvnrnvyvadlteevvytsemalkwitkgeksrhyge
tkmnqrssrshtifrmilesreksvkvshlnlvdlagseraalkegcninrslfilgqvi
kklsdgqvggfinyrdskltrilqnslggnaktriictitpvsfdetltalqfastakym
kntpyvnevs