PDB entry 1sy6

View 1sy6 on RCSB PDB site
Description: Crystal Structure of CD3gammaepsilon Heterodimer in Complex with OKT3 Fab Fragment
Class: signaling protein/antibiotic
Keywords: CD3 gamma, CD3 epsilon, OKT3 Fab, signaling protein/antibiotic COMPLEX
Deposited on 2004-03-31, released 2004-05-25
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.211
AEROSPACI score: -1.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: T-cell surface glycoprotein CD3 gamma/epsilon chain
    Species: Homo sapiens [TaxId:9606]
    Gene: CD3G, T3G, CD3E, T3E
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1sy6a1, d1sy6a2
  • Chain 'H':
    Compound: OKT3 Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1SY6 (0-218)
    Domains in SCOPe 2.03: d1sy6h1, d1sy6h2
  • Chain 'L':
    Compound: OKT3 Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 1SY6 (0-212)
    Domains in SCOPe 2.03: d1sy6l1, d1sy6l2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sy6A (A:)
mqsikgnhlvkvydyqedgsvlltcdaeaknitwfkdgkmigfltedkkkwnlgsnakdp
rgmyqckgsqnkskplqvyyrmgsaddakkdaakkddakkddakkdgsdgneemggitqt
pykvsisgttviltcpqypgseilwqhndkniggdeddknigsdedhlslkefseleqsg
yyvcyprgskpedanfylylrarv

    Sequence, based on observed residues (ATOM records): (download) 
    >1sy6A (A:)
mqsikgnhlvkvydyqedgsvlltcdaeaknitwfkdgkmigfltedkkkwnlgsnakdp
rgmyqckgsqnkskplqvyyrmqtpykvsisgttviltcpqypgseilwqhndkniggde
ddknigsdedhlslkefseleqsgyyvcyprgskpedanfylylrarv

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sy6H (H:)
qvqlqqsgaelarpgasvkmsckasgytftrytmhwvkqrpgqglewigyinpsrgytny
nqkfkdkatlttdkssstaymqlssltsedsavyycaryyddhycldywgqgttltvssa
kttapsvyplapvcggttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsdl
ytlsssvtvtsstwpsqsitcnvahpasstkvdkkiepr

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sy6L (L:)
qivltqspaimsaspgekvtmtcsasssvsymnwyqqksgtspkrwiydtsklasgvpah
frgsgsgtsysltisgmeaedaatyycqqwssnpftfgsgtkleinradtaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec