PDB entry 1sqx

View 1sqx on RCSB PDB site
Description: Crystal Structure Analysis of Bovine Bc1 with Stigmatellin A
Class: oxidoreductase
Keywords: cytochrome bc1, Qo inhibitor, membrane protein, electron transport, OXIDOREDUCTASE
Deposited on 2004-03-21, released 2005-09-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquinol-cytochrome-c reductase complex core protein I, mitochondrial precursor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxa1, d1sqxa2
  • Chain 'B':
    Compound: Ubiquinol-cytochrome-c reductase complex core protein 2, mitochondrial precursor
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxb1, d1sqxb2
  • Chain 'C':
    Compound: cytochrome b
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxc1, d1sqxc2
  • Chain 'D':
    Compound: Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP) [Contains: Ubiquinol-cytochrome c reductase 8 kDa protein (Complex III subunit IX)]
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxd1, d1sqxd2
  • Chain 'E':
    Compound: Cytochrome c1, heme protein, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxe1, d1sqxe2
  • Chain 'F':
    Compound: Ubiquinol-cytochrome c reductase complex 11 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxf_
  • Chain 'G':
    Compound: Ubiquinol-cytochrome c reductase complex 14 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxg_
  • Chain 'H':
    Compound: Ubiquinol-cytochrome c reductase complex 7.2 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxh_
  • Chain 'I':
    Compound: ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxi_
  • Chain 'J':
    Compound: Ubiquinol-cytochrome c reductase complex 6.4 kDa protein
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxj_
  • Chain 'K':
    Compound: Ubiquinol-cytochrome c reductase iron-sulfur subunit, mitochondrial precursor (EC 1.10.2.2) (Rieske iron-sulfur protein) (RISP) [Contains: Ubiquinol-cytochrome c reductase 8 kDa protein (Complex III subunit IX)]
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sqxk_
  • Heterogens: UQ2, HEC, SMA, FES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sqxA (A:)
tatyaqalqsvpetqvsqldnglrvaseqssqptctvgvwidagsryeseknngagyfve
hlafkgtknrpgnalekevesmgahlnaystrehtayyikalskdlpkavelladivqnc
sledsqiekerdvilqelqendtsmrdvvfnylhatafqgtplaqsvegpsenvrklsra
dlteylsrhykaprmvlaaagglehrqlldlaqkhfsglsgtydedavptlspcrftgsq
ichredglplahvaiavegpgwahpdnvalqvanaiighydctygggahlssplasiaat
nklcqsfqtfnicyadtgllgahfvcdhmsiddmmfvlqgqwmrlctsatesevlrgknl
lrnalvshldgttpvcedigrslltygrriplaewesriaevdarvvrevcskyfydqcp
avagfgpieqlpdynrirsgmfwlrf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sqxB (B:)
slkvapkvkateapagvpphpqdleftrlpnglviaslenyapasriglfikagsryens
nnlgtshllrlasslttkgassfkitrgieavggklsvtstrenmaytveclrddvdilm
efllnvttapefrrwevaalqpqlridkavalqnpqahvienlhaaayrnalanslycpd
yrigkvtpvelhdyvqnhftsarmaliglgvshpvlkqvaeqflnirgglglsgakakyh
ggeireqngdslvhaalvaesaaigsaeanafsvlqhvlgagphvkrgsnatsslyqava
kgvhqpfdvsafnasysdsglfgfytisqaasagdvikaaynqvktiaqgnlsnpdvqaa
knklkagylmsvessegfldevgsqalaagsytppstvlqqidavadadvinaakkfvsg
rksmaasgnlghtpfidel

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxB (B:)
vpphpqdleftrlpnglviaslenyapasriglfikagsryensnnlgtshllrlasslt
tkgassfkitrgieavggklsvtstrenmaytveclrddvdilmefllnvttapefrrwe
vaalqpqlridkavalqnpqahvienlhaaayrnalanslycpdyrigkvtpvelhdyvq
nhftsarmaliglgvshpvlkqvaeqflnirgglglsgakakyhggeireqngdslvhaa
lvaesaaigsaeanafsvlqhvlgagphvkrgsnatsslyqavakgvhqpfdvsafnasy
sdsglfgfytisqaasagdvikaaynqvktiaqgnlsnpdvqaaknklkagylmsvesse
gfldevgsqalaagsytppstvlqqidavadadvinaakkfvsgrksmaasgnlghtpfi
del

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sqxC (C:)
mtnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtt
tafssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvill
ltvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffa
fhfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalm
llvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsili
lalipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfl
lilvlmptagtienkllkw

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxC (C:)
tnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdttt
afssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvilll
tvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffaf
hfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalml
lvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsilil
alipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfll
ilvlmptagtienkllkw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sqxD (D:)
sdlelhppsypwshrgllssldhtsirrgfqvykqvcsschsmdyvayrhlvgvcytede
akalaeevevqdgpnedgemfmrpgklsdyfpkpypnpeaaraanngalppdlsyivrar
hggedyvfslltgycepptgvslreglyfnpyfpgqaigmappiynevlefddgtpatms
qvakdvctflrwaaepehdhrkrmglkmllmmglllplvyamkrhkwsvlksrklayrpp
k

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1sqxE (E:)
shtdikvpdfsdyrrpevldstksskessearkgfsylvtatttvgvayaaknvvsqfvs
smsasadvlamskieiklsdipegknmafkwrgkplfvrhrtkkeidqeaavevsqlrdp
qhdlervkkpewviligvcthlgcvpianagdfggyycpchgshydasgrirkgpaplnl
evpsyeftsddmvivg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1sqxF (F:)
agrpavsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvf
rikraldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxF (F:)
vsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvfrikra
ldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1sqxG (G:)
grqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvyt
wgtqefekskrknpaayendr

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxG (G:)
grqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvyt
wgtqefekskrknpa

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1sqxH (H:)
gdpkeeeeeeeelvdplttvreqceqlekcvkarerlelcdervssrsqteedcteelld
flhardhcvahklfnslk

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxH (H:)
elvdplttvreqceqlekcvkarerlelcdervssrsqteedcteelldflhardhcvah
klfnslk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1sqxI (I:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrgqaa
grplvasvslnvpasvry

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxI (I:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrg

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1sqxJ (J:)
vaptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhkye
nk

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxJ (J:)
aptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhkyen

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1sqxK (K:)
mltrflgpryrqlarnwvptaslwgavgavglvwatdwrlildwvpyingkfkkdd

    Sequence, based on observed residues (ATOM records): (download) 
    >1sqxK (K:)
mltrflgpryrqlarnwvptaslwgavgavglvwatdwrlildwvpyingkfk