PDB entry 1skw

View 1skw on RCSB PDB site
Description: Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template
Class: transferase/electron transport/DNA
Keywords: DNA polymerase, fidelity, lesion bypass, thymine dimer, open, close
Deposited on 2004-03-05, released 2004-07-06
The last revision prior to the SCOP 1.75 freeze date was dated 2004-08-03, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.239
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase
    Species: Bacteriophage T7
    Gene: 5
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1skwa1, d1skwa2
  • Chain 'B':
    Compound: Thioredoxin 1
    Species: Escherichia coli
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1skwb_
  • Chain 'P':
    Compound: 5'-d(*cp*gp*ap*ap*ap*ap*cp*gp*ap*c*gp*gp*cp*cp*ap*gp*tp*gp*cp*cp*(2dt))-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*cp*(ttd)p*ap*gp*gp*cp*ap*cp*tp*gp*gp*cp*cp*gp*tp*cp*gp*tp*tp*tp*tp*cp*g)-3'
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1skwA (A:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkkpknkaq
regrepceldtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkgapvvdd
evlegvrvddpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsvnpngav
tgrathafpnlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasglelrclah
fmarfdngeyaheilngdihtknqiaaelptrdnaktfiygflygagdekigqivgagke
rgkelkkkflentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrkvhvrsp
haalntllqsagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgcrteeia
qvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

    Sequence, based on observed residues (ATOM records): (download) 
    >1skwA (A:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkkpkncel
dtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvd
dpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafp
nlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasglelrclahfmarfdnge
yaheilngdihtknqiaaelptrdnaktfiygflygagdekigqivgagkergkelkkkf
lentpaiaalresiqqtlvekwkrrwikgldgrkvhvrsphaalntllqsagalicklwi
ikteemlvekglkhgwdgdfaymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnf
rclldtegkmgpnwaich

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1skwB (B:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >1skwB (B:)
kiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.