PDB entry 1si4

View 1si4 on RCSB PDB site
Description: Crystal structure of Human hemoglobin A2 (in R2 state) at 2.2 A resolution
Class: oxygen storage/transport
Keywords: Hemoglobin A2, beta thalassemia, oxygen transport, antisickling effect, OXYGEN STORAGE/TRANSPORT COMPLEX
Deposited on 2004-02-27, released 2004-10-26
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.218
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemoglobin alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1si4a_
  • Chain 'B':
    Compound: Hemoglobin delta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1si4b_
  • Chain 'C':
    Compound: hemoglobin alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1si4c_
  • Chain 'D':
    Compound: Hemoglobin delta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1si4d_
  • Heterogens: CYN, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1si4A (A:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1si4B (B:)
vhltpeektavnalwgkvnvdavggealgrllvvypwtqrffesfgdlsspdavmgnpkv
kahgkkvlgafsdglahldnlkgtfsqlselhcdklhvdpenfrllgnvlvcvlarnfgk
eftpqmqaayqkvvagvanalahkyh

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1si4C (C:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1si4D (D:)
vhltpeektavnalwgkvnvdavggealgrllvvypwtqrffesfgdlsspdavmgnpkv
kahgkkvlgafsdglahldnlkgtfsqlselhcdklhvdpenfrllgnvlvcvlarnfgk
eftpqmqaayqkvvagvanalahkyh