PDB entry 1sh9

View 1sh9 on RCSB PDB site
Description: Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease
Class: hydrolase/hydrolase inhibitor
Keywords: HIV-1 protease, non-active site mutations, active site mutations, ritonavir, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2004-02-25, released 2004-10-05
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.213
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (53)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.06: d1sh9a_
• Chain 'B':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
    • engineered (19)
    • engineered (31-32)
    • engineered (35)
    • engineered (53)
    • engineered (62)
    • engineered (70)
    • engineered (81)
    • engineered (83)
    • engineered (89)
  Domains in SCOPe 2.06: d1sh9b_
• Heterogens: RIT, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1sh9A (A:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkmiggiggfvkvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1sh9B (B:)
  pqitlwqrplvtikiggqlrealldtgaddtifeeislpgrwkpkmiggiggfvkvrqyd
  qipieicghkvigtvlvgptpanvigrnlmtqigctlnf