PDB entry 1s8d

View 1s8d on RCSB PDB site
Description: Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A
Class: immune system
Keywords: CTL, cytotoxic T lymphocytes, HIV, human immunodeficiency virus, MHC, major histocompatibility complex, pMHC, peptide-MHC complex, RMSD, root-mean-squared deviation, SIV, simian immunodeficiency virus, TCR, T-cell receptor, IMMUNE SYSTEM
Deposited on 2004-02-02, released 2005-09-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.19
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1s8da1, d1s8da2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1s8db_
  • Chain 'C':
    Compound: gag peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1S8D (0-8)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s8dA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwe

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s8dB (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.