PDB entry 1s78

View 1s78 on RCSB PDB site
Description: insights into erbb signaling from the structure of the erbb2- pertuzumab complex
Deposited on 2004-01-29, released 2004-04-27
The last revision prior to the SCOP 1.67 freeze date was dated 2004-04-27, with a file datestamp of 2004-04-27.
Experiment type: XRAY
Resolution: 3.25 Å
R-factor: 0.227
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s78A (A:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplnnttpvtgaspgglrelql
rslteilkggvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgs
rcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsg
icelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqev
taedgtqrcekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfd
gdpasntaplqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngays
ltlqglgiswlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrped
ecvgeglachqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclp
chpecqpqngsvtcfgpeadqcvacahykdppfcvarcpsgvkpdlsympiwkfpdeega
cqpcpincthscvdlddkgcpaeq

    Sequence, based on observed residues (ATOM records): (download) 
    >1s78A (A:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplspgglrelqlrslteilkg
gvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgsrcwgessed
cqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsgicelhcpal
vtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqevtaedgtqrc
ekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfdgdpasntap
lqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngaysltlqglgis
wlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrpedecvgeglac
hqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpqn
gsvtcfgpeadqcva

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s78B (B:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplnnttpvtgaspgglrelql
rslteilkggvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgs
rcwgessedcqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsg
icelhcpalvtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqev
taedgtqrcekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfd
gdpasntaplqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngays
ltlqglgiswlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrped
ecvgeglachqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclp
chpecqpqngsvtcfgpeadqcvacahykdppfcvarcpsgvkpdlsympiwkfpdeega
cqpcpincthscvdlddkgcpaeq

    Sequence, based on observed residues (ATOM records): (download) 
    >1s78B (B:)
tqvctgtdmklrlpaspethldmlrhlyqgcqvvqgnleltylptnaslsflqdiqevqg
yvliahnqvrqvplqrlrivrgtqlfednyalavldngdplspgglrelqlrslteilkg
gvliqrnpqlcyqdtilwkdifhknnqlaltlidtnrsrachpcspmckgsrcwgessed
cqsltrtvcaggcarckgplptdccheqcaagctgpkhsdclaclhfnhsgicelhcpal
vtyntdtfesmpnpegrytfgascvtacpynylstdvgsctlvcplhnqevtaedgtqrc
ekcskpcarvcyglgmehlrevravtsaniqefagckkifgslaflpesfdgdpasntap
lqpeqlqvfetleeitgylyisawpdslpdlsvfqnlqvirgrilhngaysltlqglgis
wlglrslrelgsglalihhnthlcfvhtvpwdqlfrnphqallhtanrpedecvgeglac
hqlcarghcwgpgptqcvncsqflrgqecveecrvlqglpreyvnarhclpchpecqpqn
gsvtcfgpeadqcvacahykdppfcvar

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s78C (C:)
diqmtqspsslsasvgdrvtitckasqdvsigvawyqqkpgkapklliysasyrytgvps
rfsgsgsgtdftltisslqpedfatyycqqyyiypytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1s78D (D:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrqapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >1s78D (D:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrqapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s78E (E:)
diqmtqspsslsasvgdrvtitckasqdvsigvawyqqkpgkapklliysasyrytgvps
rfsgsgsgtdftltisslqpedfatyycqqyyiypytfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1s78F (F:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrqapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkth

    Sequence, based on observed residues (ATOM records): (download) 
    >1s78F (F:)
evqlvesggglvqpggslrlscaasgftftdytmdwvrqapgkglewvadvnpnsggsiy
nqrfkgrftlsvdrskntlylqmnslraedtavyycarnlgpsfyfdywgqgtlvtvssa
stkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc