PDB entry 1s5h

View 1s5h on RCSB PDB site
Description: Potassium Channel Kcsa-Fab Complex T75C mutant in K+
Class: membrane protein
Keywords: K+ CHANNEL, PROTEIN-ANTIBODY FAB COMPLEX, selectivity filter, ion occupancy
Deposited on 2004-01-20, released 2004-05-18
The last revision prior to the SCOP 1.75 freeze date was dated 2004-05-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.222
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody fab fragment light chain
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1s5ha1, d1s5ha2
  • Chain 'B':
    Compound: antibody fab fragment heavy chain
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d1s5hb1, d1s5hb2
  • Chain 'C':
    Compound: Voltage-gated potassium channel
    Species: Streptomyces coelicolor, and Streptomyces lividans
    Gene: KCSA, SKC1, SCO7660, SC10F4.33
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q54397 (Start-123)
      • engineered (74)
    Domains in SCOP 1.75: d1s5hc_
  • Heterogens: K, DGA, F09, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s5hA (A:)
dilltqspailsvspgervsfscrasqsigtdihwyqqrtngsprllikyasesisgips
rfsgsgsgtdftlsinsvesedianyycqqsnrwpftfgsgtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrn

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5hA (A:)
dilltqspailsvspgervsfscrasqsigtdihwyqqrtngsprllikyasesisgips
rfsgsgsgtdftlsinsvesedianyycqqsnrwpftfgsgtkleikradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5hB (B:)
qvqlqqpgaelvkpgasvklsckasgytftsdwihwvkqrpghglewigeiipsygrany
nekiqkkatltadkssstafmqlssltsedsavyycarergdgyfavwgagttvtvssak
ttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdly
tlsssvtvpssswpsetvtcnvahpasstkvdkkivprd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1s5hC (C:)
mapmlsgllarlvklllgrhgsalhwraagaatvllvivllagsylavlaergapgaqli
typralwwsvetatcvgygdlypvtlwgrlvavvvmvagitsfglvtaalatwfvgreqe
rrgh

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5hC (C:)
salhwraagaatvllvivllagsylavlaergapgaqlitypralwwsvetatcvgygdl
ypvtlwgrlvavvvmvagitsfglvtaalatwfvgreqerrgh