PDB entry 1s4b

View 1s4b on RCSB PDB site
Description: Crystal structure of human thimet oligopeptidase.
Class: hydrolase
Keywords: Zinc metallopeptidase domain, HYDROLASE
Deposited on 2004-01-15, released 2004-07-20
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'P':
    Compound: Thimet oligopeptidase
    Species: Homo sapiens [TaxId:9606]
    Gene: THOP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52888
      • engineered (230)
      • engineered (237)
    Domains in SCOPe 2.05: d1s4bp_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1s4bP (P:)
spcsvvndlrwdlsaqqieertrelieqtkrvydqvgtqefedvsyestlkaladvevty
tvqrnildfpqhvspskdirtasteadkklsefdvemsmredvyqrivwlqekvqkdslr
peaarylerliklgrrnglhlpretqenikrikkklsllcidfnknlnedttflpftlqe
lgglpedflnslekmedgklkvtlkyphyfpllkkchvpetrrkveeafnsrckeensai
lkelvtlraqksrllgfhthadyvlemnmaktsqtvatfldelaqklkplgeqeravile
lkraecerrglpfdgrirawdmryymnqveetrycvdqnllkeyfpvqvvthgllgiyqe
llglafhheegasawhedvrlytardaasgevvgkfyldlypregkyghaacfglqpgcl
rqdgsrqiaiaamvanftkptadapsllqhdevetyfhefghvmhqlcsqaefamfsgth
verdfveapsqmlenwvweqepllrmsrhyrtgsavprellekliesrqantglfnlrqi
vlakvdqalhtqtdadpaeeyarlcqeilgvpatpgtnmpatfghlaggydaqyygylws
evysmdmfhtrfkqegvlnskvgmdyrscilrpggsedasamlrrflgrdpkqdafllsk
glqvggcepepqvc

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4bP (P:)
lrwdlsaqqieertrelieqtkrvydqvgtqefedvsyestlkaladvevtytvqrnild
fpqhvspskdirtasteadkklsefdvemsmredvyqrivwlqekvqkdslrpeaaryle
rliklgrrnglhlpretqenikrikkklsllcidfnknlnedttflpftlqelgglpedf
lnslekmedgklkvtlkyphyfpllkkchvpetrrkveeafnsrckeensailkelvtlr
aqksrllgfhthadyvlemnmaktsqtvatfldelaqklkplgeqeravilelkraecer
rglpfdgrirawdmryymnqveetrycvdqnllkeyfpvqvvthgllgiyqellglafhh
eegasawhedvrlytardaasgevvgkfyldlypregkyghaacfglqpgclrqdgsrqi
aiaamvanftkptadapsllqhdevetyfhefghvmhqlcsqaefamfsgthverdfvea
psqmlenwvweqepllrmsrhyrtgsavprellekliesrqantglfnlrqivlakvdqa
lhtqtdadpaeeyarlcqeilgvpatpgtnmpatfghlaggydaqyygylwsevysmdmf
htrfkqegvlnskvgmdyrscilrpggsedasamlrrflgrdpkqdafllskgl