PDB entry 1s26

View 1s26 on RCSB PDB site
Description: Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site
Class: toxin,lyase/metal binding protein
Keywords: ampcpp, edema factor, calmodulin, toxin,lyase/metal binding protein complex
Deposited on 2004-01-08, released 2004-04-13
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.264
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA, PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26a_
  • Chain 'B':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA, PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26b_
  • Chain 'C':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA, PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26c_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CAM1, CALM, CAM , CALM2, CAM2, CAMB , CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26d_
  • Chain 'E':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CAM1, CALM, CAM , CALM2, CAM2, CAMB , CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26e_
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM1, CAM1, CALM, CAM , CALM2, CAM2, CAMB , CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1s26f_
  • Heterogens: CA, YB, APC

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s26A (A:)
dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
iefkllykqlnftenetdnfevfqkiidek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26A (A:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrsssvkkiagylsdyynsanhifsqekkrkisifrgiqay
neienvlkskqiapeyknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevf
qkiid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s26B (B:)
dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
iefkllykqlnftenetdnfevfqkiidek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26B (B:)
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
tipsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiapeyknyf
qylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1s26C (C:)
dridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnv
hgkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlri
eelkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfn
wrnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvt
nllikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekd
neifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpit
kakintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanh
ifsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksn
iefkllykqlnftenetdnfevfqkiidek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26C (C:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
lykqlnftenetdnfevfqkiid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1s26D (D:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26D (D:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1s26E (E:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26E (E:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1s26F (F:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmtak

    Sequence, based on observed residues (ATOM records): (download) 
    >1s26F (F:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta