PDB entry 1riw
View 1riw on RCSB PDB site
Description: Thrombin in complex with natural product inhibitor Oscillarin
Class: hydrolase/hydrolase inhibitor
Keywords: protease, Thrombin, inhibitor complex, oscillarin, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on
2003-11-18, released
2004-11-09
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: 0.213
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Thrombin light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1riw.1 - Chain 'B':
Compound: thrombin heavy chain, B
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1riw.1 - Chain 'C':
Compound: thrombin heavy chain, C
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1riw.1 - Chain 'D':
Compound: hirudin iib
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: NAG, NA, OSC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1riwA (A:)
tfgsgeadcglrplfekksledkterellesyidgr
Sequence, based on observed residues (ATOM records): (download)
>1riwA (A:)
adcglrplfekksledkterellesyi
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1riwB (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlket
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1riwC (C:)
gqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmksp
fnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>1riwC (C:)
gqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmksp
fnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidq
- Chain 'D':
No sequence available.