PDB entry 1r78

View 1r78 on RCSB PDB site
Description: CDK2 complex with a 4-alkynyl oxindole inhibitor
Class: transferase
Keywords: cyclin dependent kinase, serine/threonine protein kinase, oxindole
Deposited on 2003-10-20, released 2004-01-20
The last revision prior to the SCOP 1.75 freeze date was dated 2004-03-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.22
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1r78a_
  • Heterogens: FMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r78A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1r78A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfgvtlwyrapeillgckyystavdiwslgcifaemvtrralfpg
dseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsq
mlhydpnkrisakaalahpffqdvtkpvphlrl