PDB entry 1r5k

View 1r5k on RCSB PDB site
Description: Human Estrogen Receptor alpha Ligand-Binding Domain In Complex With GW5638
Class: DNA binding protein
Keywords: Alpha helix, helical sandwich, DNA BINDING PROTEIN
Deposited on 2003-10-10, released 2004-11-23
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.208
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1 OR NR3A1 OR ESR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1r5ka_
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1 OR NR3A1 OR ESR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1r5kb_
  • Chain 'C':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1 OR NR3A1 OR ESR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1r5kc_
  • Heterogens: GW5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r5kA (A:)
mdpmikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladre
lvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrn
qgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekd
hihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknv
vplydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >1r5kA (A:)
lalsltadqmvsalldaeppilyseydfseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemld

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1r5kB (B:)
mdpmikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladre
lvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrn
qgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekd
hihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknv
vplydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >1r5kB (B:)
lalsltadqmvsalldaeppilyseydfseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1r5kC (C:)
mdpmikrskknslalsltadqmvsalldaeppilyseydptrpfseasmmglltnladre
lvhminwakrvpgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrn
qgkcvegmveifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekd
hihrvldkitdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknv
vplydlllemldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >1r5kC (C:)
lalsltadqmvsalldaeppilyseydfseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlihl
makagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml