PDB entry 1r5i

View 1r5i on RCSB PDB site
Description: Crystal structure of the MAM-MHC complex
Class: immune system
Keywords: superantigen, MHC, MAM, complex, IMMUNE SYSTEM
Deposited on 2003-10-10, released 2004-03-16
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.238
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01903 (0-180)
      • modified residue (22)
      • modified residue (35)
      • modified residue (72)
    Domains in SCOPe 2.05: d1r5ia1, d1r5ia2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1r5ib1, d1r5ib2
  • Chain 'C':
    Compound: Hemagglutinin peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Superantigen
    Species: Mycoplasma arthritidis [TaxId:2111]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q48898 (3-215)
      • cloning artifact (2)
    Domains in SCOPe 2.05: d1r5id_
  • Chain 'E':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01903 (0-180)
      • modified residue (22)
      • modified residue (35)
      • modified residue (72)
    Domains in SCOPe 2.05: d1r5ie1, d1r5ie2
  • Chain 'F':
    Compound: HLA class II histocompatibility antigen, DRB1-1 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1r5if1, d1r5if2
  • Chain 'G':
    Compound: Hemagglutinin peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Superantigen
    Species: Mycoplasma arthritidis [TaxId:2111]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q48898 (3-215)
      • cloning artifact (2)
    Domains in SCOPe 2.05: d1r5ih_
  • Heterogens: PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1r5iA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    d
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1r5iB (B:)
    gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
    gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1r5iD (D:)
    lgsmklrvenpkkaqkhfvqnlnnvvftnkelediynlsnkeetkevlklfklkvnqfyr
    hafgivndynglleykeifnmmflklsvvfdtqrkeannveqikrniaildeimakadnd
    lsyfisqnknfqelwdkavkltkemkiklkgqkldlrdgevainkvrelfgsdknvkelw
    wfrsllvkgvylikryyegdielkttsdfakavfed
    

    Sequence, based on observed residues (ATOM records): (download)
    >1r5iD (D:)
    smklrvenpkkaqkhfvqnlnnvvftnkelediynlsnkeetkevlklfklkvnqfyrha
    fgivndynglleykeifnmmflklsvvfdtqrkeannveqikrniaildeimakadndls
    yfisqnknfqelwdkavkltkemkiklkgqkldlrdgevainkvrelfgsdknvkelwwf
    rsllvkgvylikryyegdielkttsdfakavfed
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1r5iE (E:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    d
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1r5iF (F:)
    gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
    gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1r5iH (H:)
    lgsmklrvenpkkaqkhfvqnlnnvvftnkelediynlsnkeetkevlklfklkvnqfyr
    hafgivndynglleykeifnmmflklsvvfdtqrkeannveqikrniaildeimakadnd
    lsyfisqnknfqelwdkavkltkemkiklkgqkldlrdgevainkvrelfgsdknvkelw
    wfrsllvkgvylikryyegdielkttsdfakavfed
    

    Sequence, based on observed residues (ATOM records): (download)
    >1r5iH (H:)
    smklrvenpkkaqkhfvqnlnnvvftnkelediynlsnkeetkevlklfklkvnqfyrha
    fgivndynglleykeifnmmflklsvvfdtqrkeannveqikrniaildeimakadndls
    yfisqnknfqelwdkavkltkemkiklkgqkldlrdgevainkvrelfgsdknvkelwwf
    rsllvkgvylikryyegdielkttsdfakavfed