PDB entry 1qx7

View 1qx7 on RCSB PDB site
Description: Crystal structure of apoCaM bound to the gating domain of small conductance Ca2+-activated potassium channel
Class: signaling protein
Keywords: apoCalmodulin, SK channel, small conductance Ca2+ activated K+ channel, CaMBD, gating domain, Ca2+-activated gating, functioanl bipartism, SIGNALING PROTEIN
Deposited on 2003-09-04, released 2004-08-31
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3.09 Å
R-factor: 0.286
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CALM1, CAM1, CALM, CAM, CALM2, CAM2, CAMB, CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62161
      • modified residue (35)
      • modified residue (50)
      • modified residue (70-71)
      • modified residue (75)
      • modified residue (108)
      • modified residue (123)
      • modified residue (143-144)
    Domains in SCOPe 2.02: d1qx7a_
  • Chain 'B':
    Compound: calmodulin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CALM1, CAM1, CALM, CAM, CALM2, CAM2, CAMB, CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62161 (0-End)
      • modified residue (35)
      • modified residue (50)
      • modified residue (70-71)
      • modified residue (75)
      • modified residue (108)
      • modified residue (123)
      • modified residue (143-144)
    Domains in SCOPe 2.02: d1qx7b_
  • Chain 'D':
    Compound: Small conductance calcium-activated potassium channel protein 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: KCNN2
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: calmodulin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CALM1, CAM1, CALM, CAM, CALM2, CAM2, CAMB, CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62161
      • modified residue (35)
      • modified residue (50)
      • modified residue (70-71)
      • modified residue (75)
      • modified residue (108)
      • modified residue (123)
      • modified residue (143-144)
    Domains in SCOPe 2.02: d1qx7i_
  • Chain 'M':
    Compound: calmodulin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CALM1, CAM1, CALM, CAM, CALM2, CAM2, CAMB, CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62161
      • modified residue (35)
      • modified residue (50)
      • modified residue (70-71)
      • modified residue (123)
      • modified residue (143-144)
    Domains in SCOPe 2.02: d1qx7m_
  • Chain 'R':
    Compound: calmodulin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: CALM1, CAM1, CALM, CAM, CALM2, CAM2, CAMB, CALM3, CAM3, CAMC
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62161
      • modified residue (35)
      • modified residue (50)
      • modified residue (70-71)
      • modified residue (75)
      • modified residue (108)
      • modified residue (123)
      • modified residue (143-144)
    Domains in SCOPe 2.02: d1qx7r_

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1qx7A (A:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qx7A (A:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1qx7B (B:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qx7B (B:)
    adqlteeqiaefkeafslfgtittkelgtvmrslgqnpteaelqdminevdaidfpeflt
    mmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdemireadi
    dgdgqvnyeefvqmmt
    

  • Chain 'D':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1qx7I (I:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qx7I (I:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmt
    

  • Chain 'M':
    Sequence, based on SEQRES records: (download)
    >1qx7M (M:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qx7M (M:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmseeeireafngyiskltdeevdemireadidgdgqvnyeefvqmmta
    

  • Chain 'R':
    Sequence, based on SEQRES records: (download)
    >1qx7R (R:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmtak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qx7R (R:)
    dqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgng
    tidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeev
    demireadidgdgqvnyeefvqmmt