PDB entry 1qx4

View 1qx4 on RCSB PDB site
Description: Structrue of S127P mutant of cytochrome b5 reductase
Class: oxidoreductase
Keywords: methemoglobinemia, flavin flexibility, OXIDOREDUCTASE
Deposited on 2003-09-04, released 2004-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.207
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nadh-cytochrome b5 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: DIA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20070 (6-273)
      • cloning artifact (4-5)
      • conflict (25)
      • conflict (88)
      • engineered (100)
    Domains in SCOPe 2.08: d1qx4a1, d1qx4a2, d1qx4a3
  • Chain 'B':
    Compound: nadh-cytochrome b5 reductase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: DIA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P20070 (6-273)
      • cloning artifact (4-5)
      • conflict (25)
      • conflict (88)
      • engineered (100)
    Domains in SCOPe 2.08: d1qx4b1, d1qx4b2, d1qx4b3
  • Heterogens: FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qx4A (A:)
mhhhhmitlenpdikyplrlidkeilshdtrrfrfalpspqhilglpigqhiylstridg
nlvirpytpvssdddkgfvdlvvkvyfkethpkfpaggkmpqylenmnigdtiefrgpng
llvyqgkgkfairadkksnpvvrtvksvgmiaggtgitpmlqviravlkdpndhtvcyll
fanqsekdillrpeleelrnehssrfklwytvdkapdawdysqgfvneemirdhlpppge
etlilmcgpppmiqfaclpnlervghpkercftf

    Sequence, based on observed residues (ATOM records): (download) 
    >1qx4A (A:)
hmitlenpdikyplrlidkeilshdtrrfrfalpspqhilglpigqhiylstridgnlvi
rpytpvssdddkgfvdlvvkvyfkeaggkmpqylenmnigdtiefrgpngllvyqgkgkf
airadkksnpvvrtvksvgmiaggtgitpmlqviravlkdpndhtvcyllfanqsekdil
lrpeleelrnehssrfklwytvdkapdawdysqgfvneemirdhlpppgeetlilmcgpp
pmiqfaclpnlervghpkercftf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qx4B (B:)
mhhhhmitlenpdikyplrlidkeilshdtrrfrfalpspqhilglpigqhiylstridg
nlvirpytpvssdddkgfvdlvvkvyfkethpkfpaggkmpqylenmnigdtiefrgpng
llvyqgkgkfairadkksnpvvrtvksvgmiaggtgitpmlqviravlkdpndhtvcyll
fanqsekdillrpeleelrnehssrfklwytvdkapdawdysqgfvneemirdhlpppge
etlilmcgpppmiqfaclpnlervghpkercftf

    Sequence, based on observed residues (ATOM records): (download) 
    >1qx4B (B:)
hmitlenpdikyplrlidkeilshdtrrfrfalpspqhilglpigqhiylstridgnlvi
rpytpvssdddkgfvdlvvkvyfkeaggkmpqylenmnigdtiefrgpngllvyqgkgkf
airadkksnpvvrtvksvgmiaggtgitpmlqviravlkdpndhtvcyllfanqsekdil
lrpeleelrnehssrfklwytvdkapdawdysqgfvneemirdhlpppgeetlilmcgpp
pmiqfaclpnlervghpkercftf