PDB entry 1qtn
View 1qtn on RCSB PDB site
Description: crystal structure of the complex of caspase-8 with the tetrapeptide inhibitor ace-ietd-aldehyde
Class: hydrolase/hydrolase inhibitor
Keywords: apoptosis, dithiane-diol, caspase, cysteine-protease, hydrolase-hydrolase inhibitor complex
Deposited on
1999-06-28, released
2000-09-20
The last revision prior to the SCOPe 2.06 freeze date was dated
2012-04-04, with a file datestamp of
2012-03-30.
Experiment type: XRAY
Resolution: 1.2 Å
R-factor: 0.166
AEROSPACI score: 0.82
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: caspase-8
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1qtn.1 - Chain 'B':
Compound: caspase-8
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1qtn.1 - Chain 'C':
Compound: acetyl-ile-glu-thr-asp-aldehyde
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: DTD, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1qtnA (A:)
spreqdsesqtldkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagal
tttfeelhfeikphddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqe
apiyeltsqftglkcpslagkpkvffiqacqgdnyqkgipvetd
Sequence, based on observed residues (ATOM records): (download)
>1qtnA (A:)
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqkgipvetd
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1qtnB (B:)
lsspqtryipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercprgddiltilt
evnyevsnkddkknmgkqmpqptftlrkklvfpsd
Sequence, based on observed residues (ATOM records): (download)
>1qtnB (B:)
tryipdeadfllgmatvnncvsyrnpaegtwyiqslcqslrercprgddiltiltevnye
vsnkddkknmgkqmpqptftlrkklvfpsd
- Chain 'C':
No sequence available.