PDB entry 1qsi

View 1qsi on RCSB PDB site
Description: magnesium(II)-and zinc(II)-protoporphyrin ix's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme
Class: oxygen storage/transport
Keywords: hemoglobin; oxygen affinity; allosteric effect; metal substitution; trigger mechanism; alpha co liganded, oxygen storage/transport complex
Deposited on 1999-06-22, released 1999-07-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.186
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (hemoglobin alpha chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1qsia_
  • Chain 'B':
    Compound: protein (hemoglobin beta chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1qsib_
  • Chain 'C':
    Compound: protein (hemoglobin alpha chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1qsic_
  • Chain 'D':
    Compound: protein (hemoglobin beta chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1qsid_
  • Heterogens: HEM, CMO, HEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qsiA (A:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qsiB (B:)
vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
eftppvqaayqkvvagvanalahkyh

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qsiC (C:)
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qsiD (D:)
vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
eftppvqaayqkvvagvanalahkyh