PDB entry 1qj7
View 1qj7 on RCSB PDB site
Description: novel covalent active site thrombin inhibitors
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase-hydrolase inhibitor complex, blood coagulation-inhibitor complex, proteinase, blood coagulation, trypsin like proteinase, protease-inhibitor complex, hydrolase- hydrolase inhibitor complex
Deposited on
1999-06-22, released
2000-06-22
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-07-13, with a file datestamp of
2011-06-21.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.187
AEROSPACI score: 0.39
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1qj7.1 - Chain 'B':
Compound: thrombin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1qj7.1 - Chain 'I':
Compound: hirugen
Species: Hirudo medicinalis, synthetic [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Heterogens: GR1, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1qj7A (A:)
tfgsgeadcglrplfekksledkterellesyidgr
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1qj7B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge
- Chain 'I':
No sequence available.