PDB entry 1qj1

View 1qj1 on RCSB PDB site
Description: novel covalent active site thrombin inhibitors
Class: hydrolase/hydrolase inhibitor
Keywords: blood coagulation-inhibitor, proteinase, trypsin like proteinase, protease-inhibitor, hydrolase-hydrolase inhibitor complex
Deposited on 1999-06-21, released 2000-06-22
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-20, with a file datestamp of 2011-07-15.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.189
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1qj1.1
  • Chain 'B':
    Compound: thrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1qj1.1
  • Chain 'I':
    Compound: hirugen
    Species: Hirudo medicinalis, synthetic [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 166, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qj1A (A:)
tfgsgeadcglrplfekksledkterellesyidgr

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1qj1B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

  • Chain 'I':
    No sequence available.