PDB entry 1q6m
View 1q6m on RCSB PDB site
Description: the structure of phosphotyrosine phosphatase 1b in complex with compound 3
Class: hydrolase
Keywords: phosphatase, secondary binding site, selectivity, hydrolase
Deposited on
2003-08-13, released
2003-09-30
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.21
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein-tyrosine phosphatase, non-receptor type 1
Species: Homo sapiens [TaxId:9606]
Gene: PTPN1 OR PTP1B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1q6ma1, d1q6ma2 - Heterogens: P27, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1q6mA (A:)
mdykddddklefmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrd
vspfdhsriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvv
mlnrvmekgslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqet
reilhfhyttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcla
dtclllmdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvq
dqwkelshed
Sequence, based on observed residues (ATOM records): (download)
>1q6mA (A:)
klefmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsr
iklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmek
gslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhy
ttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmd
krkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgds