PDB entry 1q6j

View 1q6j on RCSB PDB site
Description: the structure of phosphotyrosine phosphatase 1b in complex with compound 2
Class: hydrolase
Keywords: phosphatase, secondary binding site, selectivity, hydrolase
Deposited on 2003-08-13, released 2003-09-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein-tyrosine phosphatase, non-receptor type 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN1 OR PTP1B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18031 (12-End)
      • cloning artifact (8-11)
    Domains in SCOPe 2.07: d1q6ja1, d1q6ja2
  • Heterogens: 335, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1q6jA (A:)
    mdykddddklefmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrd
    vspfdhsriklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvv
    mlnrvmekgslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqet
    reilhfhyttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcla
    dtclllmdkrkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvq
    dqwkelshed
    

    Sequence, based on observed residues (ATOM records): (download)
    >1q6jA (A:)
    klefmemekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsr
    iklhqedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmek
    gslkcaqywpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhy
    ttwpdfgvpespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmd
    krkdpssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgds