PDB entry 1q3x

View 1q3x on RCSB PDB site
Description: Crystal structure of the catalytic region of human MASP-2
Class: hydrolase
Keywords: complement, serine protease, modular structure, hinge bending, autoactivation, HYDROLASE
Deposited on 2003-08-01, released 2004-08-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.23 Å
R-factor: 0.176
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mannan-binding lectin serine protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MASP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00187 (Start-327)
      • cloning artifact (3)
    Domains in SCOPe 2.03: d1q3xa1, d1q3xa2
  • Chain 'B':
    Compound: Mannan-binding lectin serine protease 2
    Species: Homo sapiens [TaxId:9606]
    Gene: MASP2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1q3xb1, d1q3xb2
  • Heterogens: NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q3xA (A:)
asmtivdcgppddlpsgrveyitgpgvttykaviqysceetfytmkvndgkyvceadgfw
tsskgekslpvcepvcglsarttggriyggqkakpgdfpwqvlilggttaagallydnwv
ltaahavyeqkhdasaldirmgtlkrlsphytqawseavfihegythdagfdndialikl
nnkvvinsnitpiclprkeaesfmrtddigtasgwgltqrgflarnlmyvdipivdhqkc
taayekppyprgsvtanmlcaglesggkdscrgdsggalvfldseterwfvggivswgsm
ncgeagqygvytkvinyipwieniisdf

    Sequence, based on observed residues (ATOM records): (download) 
    >1q3xA (A:)
tivdcgppddlpsgrveyitgpgvttykaviqysceetfytmkvndgkyvceadgfwtss
kgekslpvcepvcglsartiyggqkakpgdfpwqvlilggttaagallydnwvltaahav
yeqkhdasaldirmgtlkrlsphytqawseavfihegythdagfdndialiklnnkvvin
snitpiclprkeaesfmrtddigtasgwgltqrgflarnlmyvdipivdhqkctaayekp
pyprgsvtanmlcaglesggkdscrgdsggalvfldseterwfvggivswgsmncgeagq
ygvytkvinyipwieniisdf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q3xB (B:)
asmtivdcgppddlpsgrveyitgpgvttykaviqysceetfytmkvndgkyvceadgfw
tsskgekslpvcepvcglsarttggriyggqkakpgdfpwqvlilggttaagallydnwv
ltaahavyeqkhdasaldirmgtlkrlsphytqawseavfihegythdagfdndialikl
nnkvvinsnitpiclprkeaesfmrtddigtasgwgltqrgflarnlmyvdipivdhqkc
taayekppyprgsvtanmlcaglesggkdscrgdsggalvfldseterwfvggivswgsm
ncgeagqygvytkvinyipwieniisdf

    Sequence, based on observed residues (ATOM records): (download) 
    >1q3xB (B:)
cgppddlpsgrveyitgpgvttykaviqysceetfytmkvndgkyvcgfwtsskgekslp
vcepvcglsarttiyggqkakpgdfpwqvlilggttaagallydnwvltaahavyeqkhd
asaldirmgtlkrlsphytqawseavfihegythdagfdndialiklnnkvvinsnitpi
clprkeaesfmrtddigtasgwgltqrgflarnlmyvdipivdhqkctaayekppyprgs
vtanmlcaglesggkdscrgdsggalvfldseterwfvggivswgsmncgeagqygvytk
vinyipwieniisdf