PDB entry 1q2w

View 1q2w on RCSB PDB site
Description: X-Ray Crystal Structure of the SARS Coronavirus Main Protease
Class: hydrolase
Keywords: SARS-CoV main protease, three domain protein (two antiparallel beta barrels, one alpha helical)
Deposited on 2003-07-26, released 2003-07-29
The last revision prior to the SCOP 1.75 freeze date was dated 2003-08-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.207
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nonstructural polyprotein pp1a
    Species: Human SARS coronavirus
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1q2wa_
  • Chain 'B':
    Compound: nonstructural polyprotein pp1a
    Species: Human SARS coronavirus
    Gene: ORF1a
    Database cross-references and differences (RAF-indexed):
    • Uniprot P59641 (2-End)
      • cloning artifact (0-1)
    Domains in SCOP 1.75: d1q2wb_
  • Heterogens: MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1q2wA (A:)
slsgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedll
irksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacy
ngspsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdle
gkfygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkyn
yepltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvr
qcsgvteg

    Sequence, based on observed residues (ATOM records): (download) 
    >1q2wA (A:)
frkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvicmlnpnyedllirksnhsf
lvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngspsgvy
qcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkfygpfv
drqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyepltqdh
vdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1q2wB (B:)
slsgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedll
irksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacy
ngspsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdle
gkfygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkyn
yepltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvr
qcsgvteg

    Sequence, based on observed residues (ATOM records): (download) 
    >1q2wB (B:)
slsgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictpnyedllirksnh
sflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngspsg
vyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkfygp
fvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyepltq
dhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcs