PDB entry 1pyx

View 1pyx on RCSB PDB site
Description: GSK-3 Beta complexed with AMP-PNP
Class: transferase
Keywords: kinase, insulin pathway
Deposited on 2003-07-09, released 2003-10-21
The last revision prior to the SCOP 1.75 freeze date was dated 2003-10-21, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.206
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen synthase kinase-3 beta
    Species: HOMO SAPIENS
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1pyxa_
  • Chain 'B':
    Compound: Glycogen synthase kinase-3 beta
    Species: HOMO SAPIENS
    Gene: GSK3B
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1pyxb_
  • Heterogens: MG, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pyxA (A:)
gpmsgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytd
tkvigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffys
sgekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgic
hrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssi
dvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqika
hpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpa
lfnfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasn
st

    Sequence, based on observed residues (ATOM records): (download) 
    >1pyxA (A:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssevylnlvldyvpetvyrvarhysrakqtlpviyvk
lymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyics
ryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptre
qiremnpfkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdel
rdpnvklpngrdtpalfnfttqelssnpplatilipphariqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pyxB (B:)
gpmsgrprttsfaesckpvqqpsafgsmkvsrdkdgskvttvvatpgqgpdrpqevsytd
tkvigngsfgvvyqaklcdsgelvaikkvlqdkrfknrelqimrkldhcnivrlryffys
sgekkdevylnlvldyvpetvyrvarhysrakqtlpviyvklymyqlfrslayihsfgic
hrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyicsryyrapelifgatdytssi
dvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptreqiremnpnytefkfpqika
hpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrdpnvklpngrdtpa
lfnfttqelssnpplatilipphariqaaastptnataasdantgdrgqtnnaasasasn
st

    Sequence, based on observed residues (ATOM records): (download) 
    >1pyxB (B:)
skvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrfk
nrelqimrkldhcnivrlryffyssevylnlvldyvpetvyrvarhysrakqtlpviyvk
lymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyics
ryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtptre
qiremfkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacahsffdelrd
pnvklpngrdtpalfnfttqelssnpplatilipphar