PDB entry 1pyd

View 1pyd on RCSB PDB site
Description: catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4 angstroms resolution
Class: lyase(carbon-carbon)
Keywords: lyase(carbon-carbon)
Deposited on 1993-03-23, released 1994-04-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pyruvate decarboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06169 (1-555)
      • conflict (54)
      • conflict (142)
      • conflict (205)
      • conflict (207)
      • conflict (537)
      • conflict (550)
    Domains in SCOPe 2.08: d1pyda1, d1pyda2, d1pyda3
  • Chain 'B':
    Compound: pyruvate decarboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06169 (1-555)
      • conflict (54)
      • conflict (142)
      • conflict (205)
      • conflict (207)
      • conflict (537)
      • conflict (550)
    Domains in SCOPe 2.08: d1pydb1, d1pydb2, d1pydb3
  • Heterogens: MG, TDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pydA (A:)
mseitlgkylferlkqvnvntvfglpgdfnlslldkiyevegmrwagnanelnaayaadg
yarikgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsissqakqlllhhtlgng
dftvfhrmsanisettamitdiatapaeidrcirttyvtqrpvylglpanlvdlnvpakl
lqtpidmslkpndaesekevidtilalvkdaknpviladaccsrhdvkaetkklidltqf
pafvtpmgkgsiseqhpryggvyvgtlskpevkeavesadlilsvgallsdfntgsfsys
yktknivefhsdhmkirnatfpgvqmkfvlqklltniadaakgykpvavpartpanaavp
astplkqewmwnqlgnflqegdvviaetgtsafginqttfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytiekli
hgpkaqyneiqgwdhlsllptfgakdyethrvattgewdkltqdksfndnskirmieiml
pvfdapqnlvkqaklt

    Sequence, based on observed residues (ATOM records): (download) 
    >1pydA (A:)
seitlgkylferlkqvnvntvfglpgdfnlslldkiyevegmrwagnanelnaayaadgy
arikgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsishhtlgngdftvfhrms
anisettamitdiatapaeidrcirttyvtqrpvylglpanlvdlnvpakllqtpidmsl
kpndaesekevidtilalvkdaknpviladaccsrhdvkaetkklidltqfpafvtpmgk
gsiseqhpryggvyvgtlskpevkeavesadlilsvgallsdktknivefhsdhmkirna
tfpgvqmkfvlqklltniadaakgykpvavpartpanaavpastplkqewmwnqlgnflq
egdvviaetgtsafginqttfpnntygisqvlwgsigfttgatlgaafaaeeidpkkrvi
lfigdgslqltvqeistmirwglkpylfvlnndgytieklihgpkaqyneiqgwdhlsll
ptfgakdyethrvattgewdkltqdksfndnskirmieimlpvfdapqnlvkqaklt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pydB (B:)
mseitlgkylferlkqvnvntvfglpgdfnlslldkiyevegmrwagnanelnaayaadg
yarikgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsissqakqlllhhtlgng
dftvfhrmsanisettamitdiatapaeidrcirttyvtqrpvylglpanlvdlnvpakl
lqtpidmslkpndaesekevidtilalvkdaknpviladaccsrhdvkaetkklidltqf
pafvtpmgkgsiseqhpryggvyvgtlskpevkeavesadlilsvgallsdfntgsfsys
yktknivefhsdhmkirnatfpgvqmkfvlqklltniadaakgykpvavpartpanaavp
astplkqewmwnqlgnflqegdvviaetgtsafginqttfpnntygisqvlwgsigfttg
atlgaafaaeeidpkkrvilfigdgslqltvqeistmirwglkpylfvlnndgytiekli
hgpkaqyneiqgwdhlsllptfgakdyethrvattgewdkltqdksfndnskirmieiml
pvfdapqnlvkqaklt

    Sequence, based on observed residues (ATOM records): (download) 
    >1pydB (B:)
seitlgkylferlkqvnvntvfglpgdfnlslldkiyevegmrwagnanelnaayaadgy
arikgmsciittfgvgelsalngiagsyaehvgvlhvvgvpsishhtlgngdftvfhrms
anisettamitdiatapaeidrcirttyvtqrpvylglpanlvdlnvpakllqtpidmsl
kpndaesekevidtilalvkdaknpviladaccsrhdvkaetkklidltqfpafvtpmgk
gsiseqhpryggvyvgtlskpevkeavesadlilsvgallsdktknivefhsdhmkirna
tfpgvqmkfvlqklltniadaakgykpvavpartpanaavpastplkqewmwnqlgnflq
egdvviaetgtsafginqttfpnntygisqvlwgsigfttgatlgaafaaeeidpkkrvi
lfigdgslqltvqeistmirwglkpylfvlnndgytieklihgpkaqyneiqgwdhlsll
ptfgakdyethrvattgewdkltqdksfndnskirmieimlpvfdapqnlvkqaklt