PDB entry 1ptu

View 1ptu on RCSB PDB site
Description: crystal structure of protein tyrosine phosphatase 1b complexed with phosphotyrosine-containing hexa-peptide (dadepyl-nh2)
Class: complex (hydrolase/peptide)
Keywords: hydrolase, acetylation, phosphorylation, peptide, complex (hydrolase/peptide) complex
Deposited on 1995-04-21, released 1996-08-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.199
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein tyrosine phosphatase 1b
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18031
      • conflict (150)
      • engineered (214)
    Domains in SCOPe 2.06: d1ptua_
  • Chain 'B':
    Compound: phosphotyrosine-containing hexa-peptide
    Database cross-references and differences (RAF-indexed):
    • PDB 1PTU (0-End)
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ptuA (A:)
memekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklh
qedndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslk
caqywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwp
dfgvpespasflnflfkvresgslspehgpvvvhssagigrsgtfcladtclllmdkrkd
pssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshedle
pppehipppprppkrilephn

    Sequence, based on observed residues (ATOM records): (download) 
    >1ptuA (A:)
emekefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhq
edndyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkc
aqywpqkeekemifedtnlkltlisediktyytvrqlelenlttqetreilhfhyttwpd
fgvpespasflnflfkvresgslspehgpvvvhssagigrsgtfcladtclllmdkrkdp
ssvdikkvllemrkfrmgliqtadqlrfsylaviegakfimgdssvqdqwkelshed

  • Chain 'B':
    No sequence available.