PDB entry 1pmv

View 1pmv on RCSB PDB site
Description: The structure of JNK3 in complex with a dihydroanthrapyrazole inhibitor
Class: transferase
Keywords: MAP kinase, apoptosis, inhibition, selectivity, TRANSFERASE
Deposited on 2003-06-11, released 2003-09-09
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.222
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 10
    Species: Homo sapiens [TaxId:9606]
    Gene: MK10_HUMAN
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1pmva_
  • Heterogens: 537, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pmvA (A:)
maskskvdnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsr
pfqnqthakrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqvi
qmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagts
fmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvie
qlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardlls
kmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliyke
vmns

    Sequence, based on observed residues (ATOM records): (download) 
    >1pmvA (A:)
dnqfysvevgdstftvlkryqnlkpigsgaqgivcaaydavldrnvaikklsrpfqnqth
akrayrelvlmkcvnhkniisllnvftpqktleefqdvylvmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglasfmmtpyvvtryy
rapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkk
lqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakris
vddalqhpyinvwydpaeveapppqqlderehtieewkeliykevmn