PDB entry 1pkq

View 1pkq on RCSB PDB site
Description: Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex
Class: immune system
Keywords: autoantibody, multiple sclerosis, EAE
Deposited on 2003-06-06, released 2003-07-15
The last revision prior to the SCOP 1.73 freeze date was dated 2003-08-19, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.25
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: (8-18C5) chimeric Fab, light chain
    Species: MUS MUSCULUS
    Gene: Ig light chain
    Domains in SCOP 1.73: d1pkqa1, d1pkqa2
  • Chain 'B':
    Compound: (8-18C5) chimeric Fab, heavy chain
    Species: MUS MUSCULUS
    Gene: Ig heavy chain
    Domains in SCOP 1.73: d1pkqb1, d1pkqb2
  • Chain 'E':
    Compound: Myelin Oligodendrocyte Glycoprotein
    Species: Rattus norvegicus
    Gene: mog
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1pkqe_
  • Chain 'F':
    Compound: (8-18C5) chimeric Fab, light chain
    Species: MUS MUSCULUS
    Gene: Ig light chain
    Domains in SCOP 1.73: d1pkqf1, d1pkqf2
  • Chain 'G':
    Compound: (8-18C5) chimeric Fab, heavy chain
    Species: MUS MUSCULUS
    Gene: Ig heavy chain
    Domains in SCOP 1.73: d1pkqg1, d1pkqg2
  • Chain 'J':
    Compound: Myelin Oligodendrocyte Glycoprotein
    Species: Rattus norvegicus
    Gene: mog
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q63345 (4-End)
      • cloning artifact (4)
      • cloning artifact (4)
    Domains in SCOP 1.73: d1pkqj_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pkqA (A:)
mkqstialallpllftpvtkadieltqspsslavsagekvtmsckssqsllnsgnqknyl
awyqqkpglppklliygastresgvpdrftgsgsgtdftltissvqaedlavyycqndhs
ypltfgagtkleikrtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdna
lqsgnsqesvteqdskdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge
c

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqA (A:)
dieltqspsslavsagekvtmsckssqsllnsgnqknylawyqqkpglppklliygastr
esgvpdrftgsgsgtdftltissvqaedlavyycqndhsypltfgagtkleikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pkqB (B:)
mkktaiaiavalagfatvaqaevklhesgaglvkpgasveisckatgytfssfwiewvkq
rpghglewigeilpgrgrtnynekfkgkatftaetssntaymqlssltsedsavyycatg
ntmvnmpywgqgttvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvsw
nsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
scsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqB (B:)
evklhesgaglvkpgasveisckatgytfssfwiewvkqrpghglewigeilpgrgrtny
nekfkgkatftaetssntaymqlssltsedsavyycatgntmvnmpywgqgttvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1pkqE (E:)
mrgsgqfrvigpghpiralvgdeaelpcrispgknatgmevgwyrspfsrvvhlyrngkd
qdaeqapeyrgrtellkesigegkvalriqnvrfsdeggytcffrdhsyqeeaavelkve
dpfywinpgrsrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqE (E:)
gsgqfrvigpghpiralvgdeaelpcrispgknatgmevgwyrspfsrvvhlyrngkdqd
aeqapeyrgrtellkesigegkvalriqnvrfsdeggytcffrdhsyqeeaavelkvedp
f

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1pkqF (F:)
mkqstialallpllftpvtkadieltqspsslavsagekvtmsckssqsllnsgnqknyl
awyqqkpglppklliygastresgvpdrftgsgsgtdftltissvqaedlavyycqndhs
ypltfgagtkleikrtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdna
lqsgnsqesvteqdskdstyslsstltlskadyekhkvyacevthqglsspvtksfnrge
c

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqF (F:)
dieltqspsslavsagekvtmsckssqsllnsgnqknylawyqqkpglppklliygastr
esgvpdrftgsgsgtdftltissvqaedlavyycqndhsypltfgagtkleikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfn

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1pkqG (G:)
mkktaiaiavalagfatvaqaevklhesgaglvkpgasveisckatgytfssfwiewvkq
rpghglewigeilpgrgrtnynekfkgkatftaetssntaymqlssltsedsavyycatg
ntmvnmpywgqgttvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvsw
nsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
scsawshpqfek

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqG (G:)
evklhesgaglvkpgasveisckatgytfssfwiewvkqrpghglewigeilpgrgrtny
nekfkgkatftaetssntaymqlssltsedsavyycatgntmvnmpywgqgttvtvssas
tkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysls
svvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1pkqJ (J:)
mrgsgqfrvigpghpiralvgdeaelpcrispgknatgmevgwyrspfsrvvhlyrngkd
qdaeqapeyrgrtellkesigegkvalriqnvrfsdeggytcffrdhsyqeeaavelkve
dpfywinpgrsrshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1pkqJ (J:)
gqfrvigpghpiralvgdeaelpcrispgknatgmevgwyrspfsrvvhlyrngkdqdae
qapeyrgrtellkesigegkvalriqnvrfsdeggytcffrdhsyqeeaavelkvedp