PDB entry 1pkd
View 1pkd on RCSB PDB site
Description: the crystal structure of ucn-01 in complex with phospho-cdk2/cyclin a
Class: transferase/cell cycle
Keywords: Protein kinase-drug complex
Deposited on
2003-06-05, released
2003-06-24
The last revision prior to the SCOP 1.73 freeze date was dated
2003-06-24, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.218
AEROSPACI score: 0.33
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Uniprot P24941 (1-296)
- cloning artifact (0)
- modified residue (160)
Domains in SCOP 1.73: d1pkda_ - Chain 'B':
Compound: cyclin a2
Species: HOMO SAPIENS
Gene: CCNA2 OR CCNA OR CCN1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1pkdb1, d1pkdb2 - Chain 'C':
Compound: Cell division protein kinase 2
Species: HOMO SAPIENS
Gene: CDK2
Database cross-references and differences (RAF-indexed):
- Uniprot P24941 (1-296)
- cloning artifact (0)
- modified residue (160)
Domains in SCOP 1.73: d1pkdc_ - Chain 'D':
Compound: cyclin a2
Species: HOMO SAPIENS
Gene: CCNA2 OR CCNA OR CCN1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1pkdd1, d1pkdd2 - Heterogens: UCN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdA (A:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdB (B:)
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsv
iagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyk
nskyhgvsllnppetlnl
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdC (C:)
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1pkdD (D:)
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaaptvnqfltqyflhqqpanckveslamflgelslidadpylkylpsv
iagaafhlalytvtgqswpeslirktgytleslkpclmdlhqtylkapqhaqqsirekyk
nskyhgvsllnppetlnl