PDB entry 1pk0

View 1pk0 on RCSB PDB site
Description: Crystal Structure of the EF3-CaM complexed with PMEApp
Class: lyase/metal binding protein
Keywords: edema factor, CaM, prodrug complex, lyase-metal binding protein COMPLEX
Deposited on 2003-06-04, released 2004-02-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.264
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0a_
  • Chain 'B':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0b_
  • Chain 'C':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0c_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0d_
  • Chain 'E':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0e_
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1pk0f_
  • Heterogens: CA, YB, EMA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1pk0A (A:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
    efkllykqlnftenetdnfevfqkiid
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0A (A:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssvkkiagylsdyynsanhifsqekkrkisifrgiqayn
    eienvlkskqiapeyknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevfq
    kiid
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1pk0B (B:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
    efkllykqlnftenetdnfevfqkiid
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0B (B:)
    dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
    ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
    kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
    ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
    ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
    inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
    tiptsaefsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiape
    yknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1pk0C (C:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
    efkllykqlnftenetdnfevfqkiid
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0C (C:)
    ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
    gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
    elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
    rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
    llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
    eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
    akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
    fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
    lykqlnftenetdnfevfqkiid
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1pk0D (D:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmta
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0D (D:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1pk0E (E:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmta
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0E (E:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1pk0F (F:)
    adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
    gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
    vdemireadidgdgqvnyeefvqmmta
    

    Sequence, based on observed residues (ATOM records): (download)
    >1pk0F (F:)
    teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
    fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
    ireadidgdgqvnyeefvqmmta