PDB entry 1pk0

View 1pk0 on RCSB PDB site
Description: Crystal Structure of the EF3-CaM complexed with PMEApp
Class: lyase/metal binding protein
Keywords: edema factor, CaM, prodrug complex, lyase-metal binding protein COMPLEX
Deposited on 2003-06-04, released 2004-02-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.264
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0a_
  • Chain 'B':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0b_
  • Chain 'C':
    Compound: calmodulin-sensitive adenylate cyclase
    Species: Bacillus anthracis [TaxId:1392]
    Gene: CYA OR PXO1-122
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0c_
  • Chain 'D':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0d_
  • Chain 'E':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0e_
  • Chain 'F':
    Compound: calmodulin
    Species: Homo sapiens [TaxId:9606]
    Gene: (CALM1 OR CAM1 OR CALM OR CAM)
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1pk0f_
  • Heterogens: CA, YB, EMA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1pk0A (A:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
efkllykqlnftenetdnfevfqkiid

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0A (A:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssvkkiagylsdyynsanhifsqekkrkisifrgiqayn
eienvlkskqiapeyknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevfq
kiid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1pk0B (B:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
efkllykqlnftenetdnfevfqkiid

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0B (B:)
dvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvhgk
ssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrieel
kengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnwrn
ievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnekqkgvtnllik
ygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdneifi
inpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitkakin
tiptsaefsvkkiagylsdyynsanhifsqekkrkisifrgiqayneienvlkskqiape
yknyfqylkeritnqvqlllthqkfkllykqlnftenetdnfevfqkiid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1pk0C (C:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqksni
efkllykqlnftenetdnfevfqkiid

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0C (C:)
ridvlkgekalkasglvpehadafkkiarelntyilfrpvnklatnliksgvatkglnvh
gkssdwgpvagyipfdqdlskkhgqqlavekgnlenkksitehegeigkiplkldhlrie
elkengiilkgkkeidngkkyyllesnnqvyefrisdennevqyktkegkitvlgekfnw
rnievmaknvegvlkpltadydlfalapslteikkqipqkewdkvvntpnslekqkgvtn
llikygierkpdstkgtlsnwqkqmldrlneavkytgytggdvvnhgteqdneefpekdn
eifiinpegefiltknwemtgrfieknitgkdylyyfnrsynkiapgnkayiewtdpitk
akintiptsaefiknlssirrssnvgvykdsgdkdefakkesvkkiagylsdyynsanhi
fsqekkrkisifrgiqayneienvlkskqiapeyknyfqylkeritnqvqlllthqkfkl
lykqlnftenetdnfevfqkiid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1pk0D (D:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmta

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0D (D:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1pk0E (E:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmta

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0E (E:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1pk0F (F:)
adqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgn
gtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdee
vdemireadidgdgqvnyeefvqmmta

    Sequence, based on observed residues (ATOM records): (download) 
    >1pk0F (F:)
teeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngtid
fpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdem
ireadidgdgqvnyeefvqmmta