PDB entry 1p8v

View 1p8v on RCSB PDB site
Description: crystal structure of the complex of platelet receptor gpib-alpha and alpha-thrombin at 2.6a
Class: membrane protein/hydrolase
Keywords: Platelet Glycoprotein receptor, Leucine Rich Repeat Domain, MEMBRANE PROTEIN-HYDROLASE COMPLEX
Deposited on 2003-05-07, released 2003-07-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.207
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: platelet glycoprotein ib alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: GP1BA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07359 (0-277)
      • engineered (20)
      • modified residue (275)
      • cloning artifact (278)
    Domains in SCOPe 2.07: d1p8va1, d1p8va2
  • Chain 'B':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1p8v.1
  • Chain 'C':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1p8v.1
  • Heterogens: NAG, MES, DFP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1p8vA (A:)
hpicevskvashlevncdkrdltalppdlpkdttilhlsenllytfslatlmpytrltql
nldrceltklqvdgtlpvlgtldlshnqlqslpllgqtlpaltvldvsfnrltslplgal
rglgelqelylkgnelktlppglltptpkleklslannnltelpagllnglenldtlllq
enslytipkgffgshllpfaflhgnpwlcnceilyfrrwlqdnaenvyvwkqgvdvkamt
snvasvqcdnsdkfpvykypgkgcptlgdegdtdlydyy

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1p8vB (B:)
eadcglrplfekksledkterellesyid

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1p8vC (C:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1p8vC (C:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlkegqpsvlqvvnlpiverpvckdstriritdnmfca
gykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkk
wiqkvidqfg