PDB entry 1p2a

View 1p2a on RCSB PDB site
Description: The structure of cyclin dependent kinase 2 (CKD2) with a trisubstituted naphthostyril inhibitor
Class: transferase
Keywords: cyclin dependent kinase, naphthostyril oxindole, TRANSFERASE
Deposited on 2003-04-15, released 2003-07-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.206
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1p2aa_
  • Heterogens: 5BN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1p2aA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1p2aA (A:)
    menfqkvekigegvvykarnkltgevvalkkirlaireisllkelnhpnivklldvihte
    nklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqnl
    lintegaikladfglavtlwyrapeillgckyystavdiwslgcifaemvtrralfpgds
    eidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsqml
    hydpnkrisakaalahpffqdvtkpvphlrl