PDB entry 1ozh

View 1ozh on RCSB PDB site
Description: The crystal structure of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.
Class: lyase
Keywords: acetolactate synthase, acetohydroxyacid synthase, thiamin diphosphate, LYASE
Deposited on 2003-04-09, released 2003-11-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.191
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: BUDB OR ILVK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ozha1, d1ozha2, d1ozha3, d1ozha4
  • Chain 'B':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: BUDB OR ILVK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ozhb1, d1ozhb2, d1ozhb3, d1ozhb4
  • Chain 'C':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: BUDB OR ILVK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ozhc1, d1ozhc2, d1ozhc3, d1ozhc4
  • Chain 'D':
    Compound: Acetolactate synthase, catabolic
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: BUDB OR ILVK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ozhd1, d1ozhd2, d1ozhd3
  • Heterogens: PO4, MG, PGE, HE3, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ozhA (A:)
mdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheana
afmaaavgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakqvhq
smdtvamfspvtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkv
lpasgapqmgaapddaidqvakliaqaknpifllglmasqpenskalrrlletshipvts
tyqaagavnqdnfsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatl
vhidvlpayeernytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelld
rrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqq
tmgvalpwaigawlvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmv
aiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaip
vdyrdnpllmgqlhlsqilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ozhA (A:)
vrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheanaafmaaa
vgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradksmdtvamfspvt
kyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkvlpasgapqmgaa
pddaidqvakliaqaknpifllglmasqpenskalrrlletshipvtstyqaagavnqdn
fsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatlvhidvlpayeer
nytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelldrgaqlnqfalhp
lrivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqqtmgvalpwaigaw
lvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvaiqeekkyqrlsg
vefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvdyrdnpllmgql
hlsqi

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ozhB (B:)
mdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheana
afmaaavgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakqvhq
smdtvamfspvtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkv
lpasgapqmgaapddaidqvakliaqaknpifllglmasqpenskalrrlletshipvts
tyqaagavnqdnfsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatl
vhidvlpayeernytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelld
rrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqq
tmgvalpwaigawlvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmv
aiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaip
vdyrdnpllmgqlhlsqilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ozhB (B:)
vrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheanaafmaaa
vgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradsmdtvamfspvtk
yaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkvlpasgapqmaapd
daidqvakliaqaknpifllglmasqpenskalrrlletshipvtstyqaagavnqdnfs
rfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatlvhidvlpayeerny
tpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelldrrgaqlnqfalhpl
rivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqqtmgvalpwaigawl
vnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvaiqeekkyqrlsgv
efgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvdyrdnpllmgqlh
lsqil

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ozhC (C:)
mdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheana
afmaaavgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakqvhq
smdtvamfspvtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkv
lpasgapqmgaapddaidqvakliaqaknpifllglmasqpenskalrrlletshipvts
tyqaagavnqdnfsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatl
vhidvlpayeernytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelld
rrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqq
tmgvalpwaigawlvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmv
aiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaip
vdyrdnpllmgqlhlsqilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ozhC (C:)
vrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheanaafmaaa
vgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakmdtvamfspv
tkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkvlpasgamgaap
ddaidqvakliaqaknpifllglmasqpenskalrrlletshipvtstyqaagavnqdnf
srfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatlvhidvlpayeern
ytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelldraqlnqfalhplr
ivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqqtmgvalpwaigawlv
nperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvaiqeekkyqrlsgve
fgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvdyrdnpllmgqlhl
sqi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ozhD (D:)
mdkqypvrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheana
afmaaavgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradkakqvhq
smdtvamfspvtkyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkv
lpasgapqmgaapddaidqvakliaqaknpifllglmasqpenskalrrlletshipvts
tyqaagavnqdnfsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatl
vhidvlpayeernytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelld
rrgaqlnqfalhplrivramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqq
tmgvalpwaigawlvnperkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmv
aiqeekkyqrlsgvefgpmdfkayaesfgakgfavesaealeptlraamdvdgpavvaip
vdyrdnpllmgqlhlsqilehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ozhD (D:)
vrqwahgadlvvsqleaqgvrqvfgipgakidkvfdslldssiriipvrheanaafmaaa
vgritgkagvalvtsgpgcsnlitgmatansegdpvvalggavkradksmdtvamfspvt
kyaievtapdalaevvsnafraaeqgrpgsafvslpqdvvdgpvsgkvlpasgapqmgaa
pddaidqvakliaqaknpifllglmasqpenskalrrlletshipvtstyqaagavnqdn
fsrfagrvglfnnqagdrllqladlvicigyspveyepamwnsgnatlvhidvlpayeer
nytpdvelvgdiagtlnklaqnidhrlvlspqaaeilrdrqhqrelldlnqfalhplriv
ramqdivnsdvtltvdmgsfhiwiarylytfrarqvmisngqqtmgvalpwaigawlvnp
erkvvsvsgdggflqssmeletavrlkanvlhliwvdngynmvaiqeekkyqrlsgvefg
pmdfkayaesfgakgfavesaealeptlraamdvdgpavvaipvdyrdnpllmgqlhl