PDB entry 1osh

View 1osh on RCSB PDB site
Description: A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR
Class: transcription
Keywords: Nuclear Receptor, Ligand Binding Domain, TRANSCRIPTION
Deposited on 2003-03-19, released 2003-09-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.215
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bile acid receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NR1H4
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q96RI1 (3-End)
      • cloning artifact (0-2)
    Domains in SCOPe 2.08: d1osha1, d1osha2
  • Heterogens: FEX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1oshA (A:)
shgeltpdqqtllhfimdsynkqrmpqeitnkilkeefsaeenfliltematnhvqvlve
ftkklpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisde
yitpmfsfyksigelkmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklck
ihqpenpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdvq

    Sequence, based on observed residues (ATOM records): (download) 
    >1oshA (A:)
shgeltpdqqtllhfimdsynkqrmpenfliltematnhvqvlveftkklpgfqtldhed
qiallkgsaveamflrsaeifnkklpsghsdlleerirnsgisdeyitpmfsfyksigel
kmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklckihqpenpqhfacllg
rltelrtfnhhhaemlmswrvndhkftpllceiwdv