PDB entry 1os9
View 1os9 on RCSB PDB site
Description: Binary enzyme-product complexes of human MMP12
Class: hydrolase
Keywords: matrix metalloproteinase, hydroxamic acid, mmp12, elastase, complex (elastase/inhibitor), metallo elastase, hydrolase
Deposited on
2003-03-19, released
2003-08-05
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.198
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9a_ - Chain 'B':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9b_ - Chain 'C':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9c_ - Chain 'D':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9d_ - Chain 'E':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9e_ - Chain 'F':
Compound: Macrophage metalloelastase
Species: Homo sapiens [TaxId:9606]
Gene: MMP12 OR HME
Database cross-references and differences (RAF-indexed):
- Uniprot P39900 (2-164)
- cloning artifact (0-1)
- engineered (67)
Domains in SCOPe 2.05: d1os9f_ - Heterogens: ZN, CA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9A (A:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9B (B:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9C (C:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9D (D:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9E (E:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>1os9F (F:)
mmgpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvf
argahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighs
lglghssdpkavmfptykyvdintfrlsaddirgiqslygdpken