PDB entry 1oiq
View 1oiq on RCSB PDB site
Description: imidazopyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation
Class: kinase
Keywords: kinase, protein kinase, transferase, serine/threonine-protein kinase, ATP-binding, cell cycle, cell division, mitosis, phosphorylation,
Deposited on
2003-06-24, released
2003-09-04
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: 0.229
AEROSPACI score: 0.32
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 1OIQ
- Uniprot P24941 (0-297)
Domains in SCOPe 2.01: d1oiqa_ - Heterogens: HDU, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1oiqA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1oiqA (A:)
menfqkvekiggvvykarnkltgevvalkkitaireisllkelnhpnivklldvihtlyl
vfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqnllinte
gaikladfgltlwyrapeillgckyystavdiwslgcifaemvtrralfpgdseidqlfr
ifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrsllsqmlhydpnkr
isakaalahpffqdvtkpvphlrl